Metabolites


Also found in: Dictionary, Thesaurus, Medical.
Related to Metabolites: Secondary metabolites

Metabolites

 

substances produced in the cells, tissues, and organs of plants and animals during intermediary metabolism and participating in the subsequent processes of assimilation and dissimilation.

In physiology and medicine, metabolites usually include the products of intracellular metabolism subject to final breakdown and removal from the organism. On entering the blood, most metabolites participate in the humoral regulation of functions, exerting specific and nonspecific influences on biochemical and physiological processes.

References in periodicals archive ?
Results show that an increase in children's urinary levels of two metabolites (3 PBA and cis-DBCA) was associated with a significant decrease in cognitive performances, whereas no association was observed for the other three metabolites (4-F-3-PBA, cis-DCCA and trans-DCCA).
5 million contract from the National Heart, Lung and Blood Institute, part of the National Institutes of Health, to establish a Metabolite Standards Synthesis Center to prepare molecules for researchers to use in the emerging field of metabolomics.
Profiles of endogenous polar metabolites and lipids were obtained using LC-MS/MS.
Most of the metabolites documented in the database are not new to science.
Since external cues such as day-night lighting patterns and nutrition influence the circadian machinery, metabolites and their relationship to signalling proteins in cells seem to be acutely tied to circadian disruptions.
utm_source=direct&utm_medium=linker&utm_campaign=Linker&id=nieto-001adr) has received a 50-game suspension after testing positive for Oxandrolone and metabolite, a performance-enhancing substance, in violation of the Minor League Drug Prevention and Treatment Program.
Based on the molecular weight of the parent compound, one can also estimate the range of molecular weights into which potential metabolites will fall.
has announced that the latest release of the Symyx Metabolite database- the largest and most comprehensive collection of drug metabolism data in the world-is now available to pharmaceutical, agrochemical, and biotechnology researchers via the Symyx Isentris(r) data access, analysis, and decision support system, as well as the Web-based DiscoveryGate(r) content platform.
The team then removed the chemicals bound to the rayon, further purified the sample, and extracted the specific 1-NP metabolites using high-performance liquid chromatography.
The AMS technology enables (1) Phase I / mass balance studies to be combined (2) absolute bioavailability studies to be conducted with less animal safety testing (3) early human metabolite profiling (4) human microdosing (Phase 0 studies) as an aid in candidate selection and (5) large molecule PK studies in humans.
Eight states currently have such "zero tolerance" laws, while the rest require additional evidence of impairment, since the presence of metabolites does not necessarily indicate that someone is unfit to drive.