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(cell and molecular biology)
The phase of mitosis during which centromeres are arranged on the equator of the spindle.
The phase of the first meiotic division when centromeric regions of homologous chromosomes come to lie equidistant on either side of the equator.



one of the stages of mitotic cellular division.

Two periods of metaphase are distinguished. The first is metakinesis, during which the chromosomes concentrate in the equatorial region of the spindle and form what is called the equatorial plate. There are a number of hypotheses regarding the mechanism of metakinesis; the trajectories of the chromosomes have been described, and maps have been drawn of the paths of the centromeres and arms of the chromosomes.

The second period of metaphase is metaphase proper, during which links are established between the chromosomal threads of the spindle and the centromeres, the chromosomes separating into chromatids. Metaphase lasts from 0.3 to 175 min in different cells. In meiosis the analogous stage of the first division is called metaphase I.

References in periodicals archive ?
SDRC is pleased that Metaphase Enterprise supports Seagate's requirement for fast worldwide sharing of product data to speed innovation," said Ron Schmitz, vice president, Metaphase Marketing and Product Planning.
EAI's philosophy to provide access to the intelligence contained in both documents and engineering graphics empowers users to realize the full benefits of enterprise-wide Metapbase PDM deployments," said Ron Schmitz, GM, Business Development and Strategic Marketing, Metaphase Technology.
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With its Rialto brand of directory-enabled software tools and services, and product data management software from Metaphase Technology, the company is focused on the architecture, implementation and lifetime support of electronic commerce and enterprise-wide client server solutions for business and government.
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Siemens Nixdorf represents the classic profile of a committed partner that will integrate and bring Metaphase products to market This is a major endorsement of both our technology and our marketing strategy of enlisting quality partners to sell and support end-user customers.
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Note to Editors: SDRC, Metaphase and I-DEAS are registered trademarks and I-DEAS Enterprise and Accelis are trademarks of Structural Dynamics Research Corporation.
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