The mixture of compound 2 (3.92 g, 5.00 mmol), potassium carbonate (2.87 g, 20.80 mmol), 2-chloroethyl methyl sulfide
(3.76 g, 34.02 mmol) and sodium iodide (3.34 g, 22.30 mmol) in anhydrous acetone (200 mL) was boiled by mixing under condenser for 3 days in a nitrogen atmosphere.
Sulfur-containing compounds, such as allicin and allyl methyl sulfide
, are known to be the main responsible constituents of Allium plants for most of their pharmacological effects [32, 33].
Table IV Causes of blood-borne halitosis Odorant Systemic diseases * Hepatic failure/liver cirrhosis * Dimethyl sulfide * Uremia/kidney failure * Dimethylamine, trimethy lamine * Diabetic ketoacidosis/diabetes mellitus * Acetone Metabolic disorders * Isolated persistent * Dimethyl sulfide hypermethioninemia * Trimethylamine * Fish odor syndrome, trimethy laminuria Medication * Disulfiram * Carbon disulfide * Dimethyl sulphoxide * Dimethyl sulfide * Cysteamine * Dimethyl sulfide Food * Garlic * Ally1 methyl sulfide
* Onion * Methyl propyl sulfide Tangerman A.