Michler's Ketone

Michler's ketone

[′mik·lərz ′kē‚tōn]
(organic chemistry)

Michler’s Ketone


di-p-dimethylaminobenzophenone; silvery-green crystals. Melting point, 179°C. Virtually insoluble in water, ether, and alcohol but dissolves in pyridine and warm benzene. Michler’s ketone (III) is prepared commercially by treating dimethylaniline (II) with phosgene (I):

Michler’s ketone is a valuable intermediate product in the manufacture of triarylmethane dyes. It was discovered in 1876 by the German chemist W. Michler.

References in periodicals archive ?
Controls also will be finalized by September 6, 2013, for Michler's ketone, a chemical intermediate used in the synthesis of a variety of dyes and pigments; butanone oxime, an anti-skinning agent used in the formulation of alkyd paints and varnishes; and n-butyl glycidyl ether, which is used as a reactive diluting agent for epoxy resins and a chemical intermediate.
Michler's ketone, butanone oxime, and n-butyl glycidyl ether were the only ones designated as toxic among the 14 substances in Batch 7 of the Challenge to Industry program.
Michler's ketone is the derivative of benzophenone, which has good photoinitiation efficiency and is widely used (28-30).
Michler's ketone itself has good photoinitiation properties because its structure contains parent benzophenone and coinitiator amine.