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A device for holding and moving fine instruments for the manipulation of microscopic specimens under a microscope.



an instrument that makes possible delicate and accurate movements of microtools and the performance of complicated operations on cells under a microscope. It consists of a system of supports equipped with screws that grip microtools (needles, pipettes, and so on) and can move them in three planes. It may be controlled pneumatically, hydraulically, mechanically, or electrically. In 1912 the Russian scientist S. S. Chakhotin used a micromanipulator (micro-operator) that he constructed for strictly localized action of an ultraviolet light beam on a cell. In the 1960’s a micromanipulator was built that had a television device, a quartz monochromator, oscilloscopes, and electronic gear that made possible remote control of the instrument and the performance of particularly complicated operations on a cell. In the USSR a composite micromanipulator has been constructed that contains mechanical, pneumatic, and piezoelectric devices, which are used as required for the problem under study.


Khokhlov, A. M., V. I. Reshetnikov, and V. M. lachin. “Printsip postroeniia i opisanie komplekta mikromanipuliatora KM-1.” Tsitologiia, 1971, vol. 13, no. 4.
Kopac, M. J. “Micromanipulators: Principles of Design, Operation and Application.” In Physical Techniques in Biological Research, vol. 5. New York-London, 1964.
el-Badry, H. M. Micromanipulators and Micromanipulation. New York-Vienna, 1963.


References in periodicals archive ?
However, in terms of volume (units), manual micromanipulator was the leading segment, accounting for about half of the overall market in 2014.
By product, the market includes antivibration tables, cryosystems, gas analyzers, imaging systems, incubators, laser systems, micromanipulator systems, ovum aspiration pumps, sperm analyzer systems, workstations, and accessories.
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5-mm-diameter optic fiber was held in a micromanipulator close to the tissue being stimulated.
The integrated EasyLift micromanipulator and QuickFlip grid holders support FEI's process for creating ultrathin TEM samples.
In this study, we reported the production of live mouse pups by a stable NT method in which donor nuclei from cumulus cells of B6D2F1 mice were directly injected into enucleated oocytes using a piezo-actuated micromanipulator.
A nurse works on a micromanipulator machine (used for fertilization) at Fortis Bloom Fertility and IVF Centre inside the Fortis hospital at Mohali in the northern Indian state of Punjab on June 13.
Each port was then connected to ground-signal-ground (CPW) Micromanipulator High Frequency Picoprobes [17] using V-band cables, which were capable of measuring up to 67 GHz.
The scientists mimicked the fluid flow in a culture dish by hooking up a tiny glass tube to a device called a micromanipulator and using it to slowly suck sperm into the tube.
Coverage includes equipment and culture media, semen analysis, semen morphology, sperm preparation, oxidative stress tests, TUNEL test, reactive oxygen species measurement, assessment of DNA fragmentation, sperm function tests, micromanipulator set-up, IMSI and PICSI sperm selection, oocyte spindle imaging system, cryopreservation and banking, and semen vitrification.
2009, Design and Optimization of an XYZ Parallel Micromanipulator with Flexure Hinges.
Some 90 selected and peer-reviewed papers from the 2009 incarnation look at such topics as a parametric modeling method for thin-walled frame parts, outer space target recognition based on image sequences, machining mechanisms of an abrasive water jet on ceramics, the disassembly design of used cars, the diversified development of scholarship in local colleges and universities, the design of a micromanipulator based on a piezo actuator, an intelligent recognition algorithm based on a mechanical seal fault feature, and an ontology-based design knowledge model.