microtubule-associated protein

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microtubule-associated protein

[¦mī·krō‚tüb·yül a¦sō·sē‚ād·ed ′prō‚tēn]

(cell and molecular biology)

A protein that enhances the rate and extent of the polymerization of intracellular microtubules or that modifies their properties once formed. Abbreviated MAP.

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References in periodicals archive ?

Upregulation of the microtubule associated protein beta III-tubulin is associated with clinical resistance to these drugs, which is what makes the Benitec- CCIA approach so promising.

Benitec Limited (ASX:BLT) and CCIA Collaborate on an RNAi Therapeutic for Lung Cancer

SG410 is an antimitotic inhibitor that was shown in Biomerk Tumorgraft models to target microtubule associated protein tau (MAPT) deficient tumors with promising results as compared to a currently marketed and leading chemotherapeutic drug.

Champions Biotechnology Partners with Do-Coop Technologies to Advance Its Novel Oncology Compound Into Biomerk Tumorgraft(TM) Testing

EML4-ALK (echinoderm microtubule associated protein like 4 - anaplastic lymphoma kinase) is a fusion protein resulting from a chromosomal translocation present in a relatively large percentage of NSCLCs (non-small cell lung cancers), a disease in which cancer cells form in the tissues of the lung.