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Our patient was diagnosed as having Gorlin-Goltz syndrome with numerous BCCs and falx cerebri calcifications, which are among the major criteria, and macrocephaly, frontal bossing, hypertelorism, and presence of medullablastoma, which are among the minor criteria.
These conditions, which were formerly listed within minor criteria according to the 2010 ASBMR diagnostic criteria, were removed from the revised diagnostic criteria.
Diagnosis of definite infective endocarditis must meet one of the following: 1) two major criteria, 2) one major with three minor criteria, or 3) five minor criteria.
The major and minor criteria follow with the point scores indicated in parentheses.
According to Modified Duke's Criteria, cases were defined as "definite" if they possessed two of the Duke major criteria, one major and three minor criteria, or five minor criteria; they were defined as "possible" if they had one major plus one minor criteria, or three minor criteria.
They include 4 major criteria and 5 minor criteria.
2,6-8,10) A positive diagnosis can be reached when patients have either (1) 2 major criteria, (2) 1 major and 2 minor criteria, or (3) 4 minor criteria.
Minor criteria Predisposing heart condition (known or found on echocardiograph) Fever, temperature >38[degrees]C Vascular phenomena, major arterial emboli, septic pulmonary infarcts, mycotic aneurysm (see at PET scan), intracranial hemorrhage, conjunctival hemorrhages, and Janeway lesions Immunologic phenomena: glomerulonephritis, Osle nodes, Roth spots, or rheumatoid factor Serologic evidence: IgG I antibodies [greater than or equal to] 800 <6,400 Diagnosis definite 1.
If a candidate takes care of at least 12 of the 16 minor criteria then he will succeed.
Patients who meet 1 major criterion only or more than 2 minor criteria are deemed to have symptoms "suggestive" of acute sinusitis.
Major criteria Minor criteria Splenomegaly > 10 cm Hepatic sinusoidal lymphocytosis IgM > 2SD of local mean Hypersplenism High titers of antimalarial Lymphocytic proliferation antibodies Clinical and immunological Normal cellular and humoral response to antimalarial drug immune response to antigenic challenge excluding Plasmodium Occurrence within families and tribes