Natural history of extensive Mongolian spots
in MPS2 (Hunter syndrome): a survey among 52 Japanese patients.
(1) Sebaceous hyperplasia, milia, Epstein's pearls and Mongolian spots
are present in a majority of neonates at birth or a few hours thereafter.
In the papillary and upper reticular dermis, dendritic melanocytes are present and surrounded by fibrous sheaths (which are not present in other dermal melanocytosis, such as blue nevus or mongolian spots
* The differential diagnosis for CMN includes cafe au lait macules, blue-gray spots (aka Mongolian spots
), nevus of Ota, nevus spilus, and vascular malformations (table).
Blue discolouration of the skin can have a multitude of causes, including Mongolian spots
, blue naevi, the naevi of Ito and Ota and metallic discolouration (1) or the use of drugs such as minocycline.
The most common site for mongolian spots
was lower back (58.4%) and gluteal region (35.2%) (Fig.
When to worry: "Mongolian spots
are completely benign and present no medical threat whatsoever," says David Green, MD, spokesperson for the American Academy of Dermatology, in Bethesda, Maryland.
The most common are cafe-au-lait spots - coffee-coloured marks found anywhere on the body - moles and bluish-grey Mongolian spots
Conditions that might be mistaken for abusive skin injuries include Mongolian spots
, coagulopathies, vasculitis, and rare connective tissue disorders such as Ehlers-Danlos syndrome.
93 children showed Mongolian spots
. The signs of miniature puberty were found in 82 children.105 children had sebaceous hyperplasia.
Pigmented naevi were the most common, with mongolian spots
in 11.7% of neonates, followed by congenital melanocytic naevi (2.7%).
The most common dermatoses were Mongolian spots
(63.2%), Epstein pearls (47.8%), sebaceous hyperplasia (44.8%), miliaria (12.8%), hypertrichosis (12%), erythema toxicum neonatorum (12%), salmon patch (12%) and impetigo (11.4%).