monoglyceride

(redirected from Monoacylglycerol)
Also found in: Dictionary, Medical.

monoglyceride

[¦män·ō′glis·ə‚rīd]
(organic chemistry)
Any of the fatty-acid glycerol esters where only one acid group is attached to the glycerol group, for example, RCOOCH2CHOHCH2OH; examples are glycerol monostearate and monolaurate; used as emulsifiers in cosmetics and lubricants.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Glycerolipids Glycerophospholipids (GLs) (GPLs) 1 MG -- 2 MG -- 3 -- -- 4 MG Lyso-GP 5 -- Lyso-GP 6 DG Lyso-GP 7 DG -- 8 -- Lyso-PI 9 DG -- 10 DG -- 11 DG -- 12 DG -- 13 TG -- 14 TG -- 15 TG Ac1PIM1 MG: monoacylglycerols; DG: diacylglycerols; TG: triacylglycerols; PG: diacylglycerophosphoglycerols; PI: diacylglycerophosphoinositols; PE: diacylglyc-erolphosphoethanolamines; PIM: phosphatidylinositol mannosides; PIM1: phosphatidylinositol monomannosides; PIM2: phosphatidylinositol dimannoside; DIM-B: phthiodiolone dimycocerosates; MA: mycolic acids; Lyso-GP: monoacylglycerophosphoglycerols; Lyso-PI: monoacylglycerophosphoinositols; Ac1PIM1: monoacylated diacylglycerophosphoinositol monomannosides.
Hohmann, "Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: effects of endocannabinoid deactivation inhibitors targeting fattyacid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics following cisplatin treatment," Pharmacological Research, vol.
Cravatt, "Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis," Cell, vol.
serine peptidase Peptide hormone processing TLL1 Tolloid like 1 Cell differentiation Troglitazone SCN4A Sodium voltage-gated Regulation of ion channel alpha subunit 4 transmembrane transport CD96 CD96 molecule Cell adhesion PCK1 Phosphoenolpyruvate Glucose metabolic process Carboxykinase 1 ADAMTS18 ADAM metallopeptidase Proteolysis with thrombospondin type 1 motif 18 MOGAT1 Monoacylglycerol Diacylglycerol O-acyltransferase 1 biosynthetic process ADRA1A Adrenoceptor alpha 1A G-protein-coupled receptor signaling pathway SCGN Secretagogin.
Other processes of degradation have also been described for 2-AG, such as monoacylglycerol lipase (MAGL) (Bisogno et al., 2005; Howlett etal., 2004).
The possible effects by which phytoestrogens reduced cholesterol in the group HL + SM are related to the modulation of intestinal cholesterol absorption and may: i) restrict cholesterol solubility in micelles, which decreases food lipid emulsification and consequently hampers lipase action and TG hydrolysis into free fatty acids monoacylglycerol and diacylglycerol (8,30); ii) compete with cholesterol for Niemann-Pick C1-like 1 protein, part of an intestinal cholesterol transport system that is located in enterocytes' apical membrane and promotes cholesterol passage through the brush border, thus decreasing intestinal absorption (31); and iii) reduce cholesterol esterification and chylomicrons synthesis within intestinal enterocytes, decreasing chylomicrons lymphatic absorption (32).
TJZL184, a monoacylglycerol lipase inhibitor, exhibited antidepressant effects by enhancing adult neurogenesis and long-term synaptic plasticity in the dentate gyrus of the hippocampus [15].
Carob oils tend to accumulate neutral lipids, including monoacylglycerol (MAG), diacylglycerol (DAG), triacylglycerol (TAG), free fatty acids (FFA), and alkyl chain.
There are three lipases expressed in skeletal muscle that are responsible for the breakdown of TAGs: monoacylglycerol lipase, adipose triglyceride lipase (ATGL), and hormone-sensitive lipase (HSL) [53].
Yamazaki et al., "Task-specific enhancement of hippocampus-dependent learning in mice deficient in monoacylglycerol lipase, the major hydrolyzing enzyme of the endocannabinoid 2-arachidonoylglycerol," Frontiers in Behavioral Neuroscience, vol.
In the former, ATGL bound on LD surface hydrolyzes TAGs to DAGs, and HSL, after translocation from cytosol to LDs, converts DAGs into 1-acylglycerols (MAGs), and finally monoacylglycerol lipase (MGL) hydrolyzes MAGs into free FAs (FFAs) and glycerol.
Iglesias et al., "[alpha]/[beta]-Hydrolase domain-6-accessible monoacylglycerol controls glucose-stimulated insulin secretion," Cell Metabolism, vol.