By applying Kolmogorov-Smirnov (Lilliefors) and Shapiro Wilk tests for normality, we evaluated the following variables: total number of metaphase cells, number and frequency of normal and abnormal metaphase cells and frequency of polyploidies, endoduplicacions and monosomies
per group in passage 1.
The most commonly involved chromosomal changes in primary MDS have been monosomies
5,7, trisomy 8, deleltions 5q, 7q, 9q and 20q (9,10).
His analyses of tissue samples from spontaneously aborted fetuses revealed a surprising number of trisomies (cells containing double contributions from one parent in addition to a normal complement of chromosomes from the other parent) and X-chromosome monosomies
(cells containing one, rather than two, sex chromosomes).
For women aged 36-41 years, the prevalence of aneuploidy, including monosomies
as well as trisomies, is 70%-80% among embryos deemed suitable for transfer based on conventional morphologic analysis.