Morquio's syndrome


Also found in: Dictionary, Thesaurus, Medical.

Morquio's syndrome

[′mȯr·kwē‚ōz ‚sin‚drōm]
(medicine)
A hereditary disease transmitted as an autosomal recessive and characterized by large quantities of keratosulfate in urine, dwarfism, and a typical facies with broad mouth, prominent maxilla, short nose, and widely spaced teeth. Also known as Brailsford-Morquio syndrome; familial osteochondrodystrophy; mucopolysaccharidosis IV.
References in periodicals archive ?
Despite having a progressive degenerative condition called Morquio's Syndrome, Kevin is bright and surprisingly fearless.
Kevin, played by Kieran Culkin, younger brother of Macauley, was born with Morquio's Syndrome, a terminal illness which stops the body's growth.
Morquio's syndrome was also considered because it often has many of the same features.
Danny Woodhouse, 16, was born with Morquio's Syndrome, which means his internal organs continue to grow but his skeleton doesn't.
Nursery nurse Julie, and husband Paul, 36, a factory manager, knew nothing of Morquio's syndrome and were stunned when first Jack and then Lewis were diagnosed.
SUPERSTAR: Our stories on Dan as a child of courage in 2001, above, and appealing for a new wheelchair in 2003 HAPPY BIRTHDAY: Morquio's Syndrome sufferer Dan Woodhouse, pictured above with his mum Sue, is celebrating his 21st birthday today
The main non-traumatic origins include rheumatoid arthritis, Down syndrome, Marfan syndrome, Morquio's syndrome, Grisel's syndrome, and after head and neck surgical manipulation (4,6,13).
A genetic defect has been identified in the N-acetyl-galactosamine-6-sulphate sulphatase (GALNS gene) in Morquio's syndrome type IVA or beta-galactosidase (GLB1 gene) in Morquio's syndrome type IVB.