Mucins


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Mucins

 

secretions from epithelial cells in the mucosa of respiratory, digestive, and urogenital tracts, as well as from the submaxillary and sublingual salivary glands. Mucins are mixtures of the carbohydrate-protein compounds known as glycoproteins and impart moisture and elasticity to the mucosa. Salivary mucins promote the moistening and adhesion of food particles for smooth passage through the esophagus. Covering the gastrointestinal mucosa, mucins provide protection from the action of proteolytic enzymes in gastric and intestinal juices. Mucins perform an overall protective function in the organism; for example, they inhibit the erythrocyte agglutination caused by the influenza virus.

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C) Neutral apical mucins in the gastric corpus with intense periodic acid-Schiff positivity (x200).
Morphology and Histology of the Pirarucu (Arapaima gigas) Digestive Tract/Morfologia e Histologia del Tubo Digestivo del Paiche (Arapaima gigas)
Intestinal goblet cells and mucins in health and disease: recent insights and progress.
Histochemical Characterization of Convict Cichlid (Amatitlania nigrofasciata) Intestinal Goblet Cells
Role of mucins in the skin during benign and malignant conditions.
The influence of luteolin on expression of epithelial MUC1 mucin in human skin fibroblasts
Fujimoto [sup][22] found that neutral mucins and sulfomucins were both significantly reduced in the piebald lethal mouse model of HSCR.
Novel Insights into the Pathogenesis of Hirschsprung's-associated Enterocolitis
The MUC5AC mucin gene expression was measured by RT-PCR.
Verticine, ebeiedine and suchengbeisine isolated from the bulbs of Fritillaria thunbergii Miq. inhibited the gene expression and production of MUC5AC mucin from human airway epithelial cells
1,4,7) The cells lack well-formed apical mucin caps, which is a useful feature to differentiate PGAs from gastric foveolar-type adenoma (Figure 1, B).
Gastric Pyloric Gland Adenoma
When the sections of parotid gland are stained with PAS stain, it was found that the acinar cells are deeply stained in SN region with magenta showing the presence of PAS positive substances like carbohydrate and neutral mucins.
Histochemical study of mucosubstances of normal human parotid salivary gland
Other mucins, in smaller quantities, are also secreted by the epithelia.
In praise of the conjunctiva
Five out of 15 LAMNs showed gross evidence of rupture with acellular mucin on the serosal surface.
Molecular profiling of appendiceal epithelial tumors using massively parallel sequencing to identify somatic mutations
24 March 2014 - A research team from Sahlgrenska Academy at the Swedish University of Gothenburg has developed a proteomic mucin profiling method able to predict with certainty of 97% which pancreatic cysts are at risk for developing into cancer, the univesity said on Friday.
Swedish scientists develop method detecting cystic precursors of pancreatic cancer
Mucins: Mucins are a group of glycosolated protein (sugar plus protein) molecules that are unique in their ability to form gels.
A sticky situation: mucus support for respiratory illnesses
Role of Intestinal mucins in Innate host defense mechanisms against pathogens.
The Bacillus subtilis and lactic acid bacteria probiotics influences intestinal mucin gene expression, histomorphology and growth performance in broilers

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