To characterize the
multipotency of the turkey TDSCs, we differentiated the tendon-derived cells for osteogenesis, chondrogenesis, and adipogenesis and found that tendonderived cells had multilineage capacity.
"We also demonstrated that when adult olfactory stem cells are transplanted into an environmental niche different from that of their origin, they demonstrate
multipotency by acquiring the phenotype of the resident cells."
Firstly, MenSCs were characterized to show their
multipotency and immunophenotype.
Kharazi et al., "DNA methylation protects hematopoietic stem cell
multipotency from myeloerythroid restriction," Nature Genetics, vol.
The adverse microenvironment of EMS horses' adipose tissue negatively affects ASC
multipotency and metabolism.
Richardson, "Human adipose-derived stem cells exhibit enhanced proliferative capacity and retain
multipotency longer than donor-matched bone marrow mesenchymal stem cells during expansion in vitro," Stem Cells International, vol.
Human ES cells possess unrestricted proliferative ability despite its
multipotency, but ethical issues always follow.
Rabbani et al., Dysregulation of Nrf2/Keap1 Redox Pathway in Diabetes Affects
Multipotency of Stromal Cells.
The
multipotency of BMSC was evaluated via differentiation into osteoblast and adipocyte according to standard staining protocols e.g.
Multipotency of CD34-presenting cells has made them useful agents for various therapeutic purposes, such as cancer, diabetes, cardiovascular diseases, and autoimmune disorders (16).
Stem cells'
multipotency is the most notable characteristic for cell transplantation therapy.
Mesenchymal cells have been proposed as promising candidates for tissue regeneration based on their easy accessibility, rapid expansion, low immunogenicity, and
multipotency. When exposed to classical chemical cocktails, MCs adopt specific phenotypes, express cell-specific markers, and exhibit functional characteristics.
