To characterize the multipotency
of the turkey TDSCs, we differentiated the tendon-derived cells for osteogenesis, chondrogenesis, and adipogenesis and found that tendonderived cells had multilineage capacity.
"We also demonstrated that when adult olfactory stem cells are transplanted into an environmental niche different from that of their origin, they demonstrate multipotency
by acquiring the phenotype of the resident cells."
Firstly, MenSCs were characterized to show their multipotency
Kharazi et al., "DNA methylation protects hematopoietic stem cell multipotency
from myeloerythroid restriction," Nature Genetics, vol.
The adverse microenvironment of EMS horses' adipose tissue negatively affects ASC multipotency
Richardson, "Human adipose-derived stem cells exhibit enhanced proliferative capacity and retain multipotency
longer than donor-matched bone marrow mesenchymal stem cells during expansion in vitro," Stem Cells International, vol.
Human ES cells possess unrestricted proliferative ability despite its multipotency
, but ethical issues always follow.
Rabbani et al., Dysregulation of Nrf2/Keap1 Redox Pathway in Diabetes Affects Multipotency
of Stromal Cells.
of BMSC was evaluated via differentiation into osteoblast and adipocyte according to standard staining protocols e.g.
of CD34-presenting cells has made them useful agents for various therapeutic purposes, such as cancer, diabetes, cardiovascular diseases, and autoimmune disorders (16).
Stem cells' multipotency
is the most notable characteristic for cell transplantation therapy.
Mesenchymal cells have been proposed as promising candidates for tissue regeneration based on their easy accessibility, rapid expansion, low immunogenicity, and multipotency
. When exposed to classical chemical cocktails, MCs adopt specific phenotypes, express cell-specific markers, and exhibit functional characteristics.