Multipotential Stem Cells

Multipotential Stem Cells

 

cells making up the continually self-renewing tissues of both adult and developing animals. In vertebrates they are found, for example, in epithelial, hemopoietic, and bony tissues. Each tissue has characteristic multipotential stem cells, distinguished by their proliferative activity and degree of specialization. Differentiated tissue cells often have common multipotential stem cells, which can develop in different directions. For example, in mammalian hemopoietic tissue, various blood cells—erythrocytes, thrombocytes, and leukocytes—are formed from common multipotential stem cells. The perpetual presence of these stem cells in an organism ensures not only the renewal of the cell population of the corresponding tissues under normal conditions, but also the replenishing of cells when they are destroyed.

REFERENCE

Zavarzin, A. A. Ocherki evoliutsionnoi gistologii krovi i soedinitel’noi tkani: Izbr. trudy, vol. 4. Moscow-Leningrad, 1953.
References in periodicals archive ?
The recombinant BMP-2 has proliferative effects on the multipotential stem cells toward the fibroblastic, osteoblast/osteocyte, and adipocyte cell lines (Yamaguchi et al, 1991 and Sigurdsson et al, 1995).
They are able to act as multipotential stem cells capable of giving rise to astrocytes, oligodendrocytes, and neurons.
(5,6) Recently, it has been postulated that hematogenous spread of multipotential stem cells occurs with eventual infiltration of various tissues and organs.
NSCs are multipotential stem cells with the capability to self-renew and can generate neurons, astrocytes, and oligodendrocytes [9].
Komaki, "Muscle satellite cells are multipotential stem cells that exhibit myogenic, osteogenic, and adipogenic differentiation," Differentiation, vol.
The jejunal villi contain the multipotential stem cells (Cheng, 1974).
Transplantation of multipotential stem cells in patients with MS is a relatively safe procedure and induces immediate immunomodulatory effects.
Rudnicki, "Muscle satellite cells are multipotential stem cells that exhibit myogenic, osteogenic, and adipogenic differentiation," Differentiation: Research in Biological Diversity, vol.
Recently, it has been postulated that the hematogenous spread of multipotential stem cells occurs with eventual infiltration of various tissues and organs.
Because they are multipotential stem cells capable of giving rise to astrocytes, oligodendrocytes, and neurons, they may be play a role in new therapies for neurodegenerative diseases.
The bone marrow is a potential source of multipotential stem cells. Bone marrow stem cells expressing hematopoietic antigens have been proven to have the capacity to differentiate into hepatocytes (33).
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