The challenge in identification of early lamina propria invasion (25) could lead to understaging of T1 disease, whereas misinterpretation of muscularis propria with muscularis mucosa
would lead to overstaging towards muscle-invasive disease.
The muscularis mucosa
, which is the last layer of the mucosa, is composed of two smooth muscle layers that are circular interiorly and longitudinal exteriorly.
Under the light microscope, the muscularis mucosa
is represented by a thin layer of smooth muscle cells lining the lower limits of the intestinal glands.
Despite being a benign lesion it can recidivate locally, possibly due to muscularis mucosa
invasion, described in 41% of the patients in a review by Montgomery et al.
The lamina propria and muscularis mucosa
of the inner mucous membranes were normal, and the vascular endothelia were regular.
Both lesions were resected, and histological examination revealed heterotopic pancreatic tissue involving the adventitia, muscularis propria, and submucosa extending to the muscularis mucosa
Occurring at the base of the glands are a few layers of smooth-muscle cells that resemble muscularis mucosa
The intestinal villous height was measured from the luminal epithelium to the muscularis mucosa
and the crypt depht, from the luminal epithelium of the crypt to the muscularis mucosa
In some cases, a lamina muscularis mucosa
underlies the lamina propria mucosae.
In addition, contraction causing partial separation of the inner and outer layers of the muscularis mucosa
added to the thickening.
He reviewed 78 cases of esophageal adenocarcinoma with invasion through the basement membrane into the lamina propria, but not through the muscularis mucosa
From the lumen to the submucosa, it consists of three sections: the epithelium, the lamina propria and the muscularis mucosa