Dx PLUS assays for gene-specific mutation testing
to aid in the selection of targeted therapy regimens.
23) In colorectal carcinoma, KRAS mutation testing
was the first genetic test employed to guide the treatment of a cancer and is currently approved by the FDA as an indication for monoclonal antibody against EGFR receptors treatment with cetuximab (Erbitux[R]) and panitumumab (Vectibix[R]).
IGNITE supports value of EGFR mutation testing
in all patients with advanced NSCLC
Sysmex Inostics GmbH is a molecular diagnostics company which provides testing for highly sensitive mutation testing
from plasma and serum samples.
Genetic counseling "increases the accuracy of risk perception; decreas- es intention for mutation testing
among women who are unlikely carriers; and decreases cancer worry, atudety, and depression," according to the guideline writers.
Second Place ($1,000 award): Ulcerated Versus Non-Ulcerated Melanoma: An Evaluation of EMT Gene Expression Patterns and Cancer Hotspot Mutation Testing
Using Ion Torrent Next-Generation Sequencing.
the relatively low cost of common mutation testing
makes it possible to offer it to a broader group of women
attempts to assess the quality of a test set by its ability to distinguish the program under test from its mutants.
Individuals known to have one of these conditions because of family history or phenotype, or because it had been identified through predictive mutation testing
, are offered lifelong surveillance with imaging analysis (e.
Over recent years, there has been a very significant increase in referrals for mutation testing
, while funding has remained unchanged.
Tests will be done through EGFR Mutation Testing
, (mutations of epidermal growth factor receptor known as EGFR), which will only be used to give mutation positive patients with non-small cell lung cancer a better treatment option versus chemotherapy.
Potentially any person could undergo mutation testing
for BRCA1 or BRCA2, or both.