Mutation Testing


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Mutation Testing

(testing)
A method to determine test set thoroughness by measuring the extent to which a test set can discriminate the program from slight variants of the program.
References in periodicals archive ?
BRCA mutation testing for breast and ovarian cancer susceptibility is advisable, especially if there is any family history of cancers.
Nevertheless, its usefulness in the field of RAS mutation testing must be considered in a different way depending on the type of cancer analyzed.
Researchers at the University of Erlangen-Nuremberg in Germany undertook an analysis of EGFR mutation testing in a cohort of patients with advanced EGFR-mutant non-small cell lung cancer (NSCLC) using cell-free DNA as a liquid biopsy on the GeneReader NGS System, and among the findings recommended further studies.
Additional content reinforces the value of mutation testing as a standard practice in monitoring patients with CML, including its importance for identifying the risk of treatment resistance.
In 'Breast cancer in high-risk Afrikaner families: Is BRCA founder mutation testing sufficient?
KRAS mutation testing in metastatic colorectal cancer.
Table 1 includes the frequency of responses related to breast cancer genetic mutation testing, diagnosis, and barriers to testing.
23) In colorectal carcinoma, KRAS mutation testing was the first genetic test employed to guide the treatment of a cancer and is currently approved by the FDA as an indication for monoclonal antibody against EGFR receptors treatment with cetuximab (Erbitux[R]) and panitumumab (Vectibix[R]).
A targeted mutation testing was recommended to the children of the patients.
GP1BA targeted mutation testing was subsequently performed and resulted in detection of 1 of 4 known PT-VWD mutations (c.
Impact of teenage oral contraceptive use in a population-based series of early-onset breast cancer cases who have undergone BRCA mutation testing.
Genetic counseling "increases the accuracy of risk perception; decreas- es intention for mutation testing among women who are unlikely carriers; and decreases cancer worry, atudety, and depression," according to the guideline writers.