Mydriatics


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Related to Mydriatics: glaucoma, Tropicamide

Mydriatics

 

substances that cause dilation of the pupil, or mydriasis, by increasing the tension of the radial fibers of the iris (sympathomimetics) or by decreasing the tension of the pupillar sphincter (M-cholinolytic substances, such as atropine, which also cause paralysis of accommodation). Mydriasis may also be caused by synthetic mydriatics.

Mydriatics are used as therapeutic agents (causing functional rest in acute inflammatory diseases and traumas of the eye) and for diagnostic purposes (for example, during examination of the fundus oculi). Mydriatics are applied in the form of solutions or ointments to the conjunctival sac of the eye. The use of mydriatics to treat glaucoma is contraindicated, since mydriatics increase intraocular pressure.

References in periodicals archive ?
Behndig, "The mydriatic effect of intracameral epinine hydrochloride," Investigative Opthalmology and Visual Science, vol.
Consequently, topical or intraocular parasympatholytic (atropine) and sympathomimetic (phenylephrine) mydriatic agents used to dilate mammalian pupils are not effective in a variety of avian species because of the high proportion of striated sphincter muscle fibers.
This study demonstrated that rocuronium bromide was an effective mydriatic agent in Hispaniolan Amazon parrots and had rapid onset and prolonged duration of action.
In MMC, one of 3 cases complicated with hypotony and early bleb leakage was managed conservatively by mydriatics and withdrawal of steroids, while the other two cases necessitated surgical intervention in the form of tight resuturing of the conjunctival flap to prevent bleb leakage.
Pupil - In all cases Pupils were Equal, Round, reacting normally to Light and Accommodation (PERLA); 6(10%) in study group and 10(16.6%)in control group had small pupils and their dilatation with mydriatic was also poor.
There were no significant differences in the demographic characteristics and ocular parameters between those who received mydriatics and those who were in the control group.
Arrhythmia before anesthesia might be related to the use of mydriatics and to anxiety.
Many potent drugs such as Glucocorticoids (4), Antimicrobials (5), Mydriatics, (6) etc are used in the management of cataract.
The first section on early principles discusses tear film physiology and drug delivery systems before delving into the details of therapeutic agents by type (including anti-bacterial agents, anti-inflammatories, anti-viral agents, antifungal agents, glaucoma treatments, local anaesthetics, anti-allergy agents, dry eye treatments, mydriatics and drug toxicity).
In a study from Rotterdam, on 6760 people acute angle closure glaucoma was precipitated in only two (0.09%) individuals of of more than 55 years of age, after use of mydriatic eye drop10.
To determine the efficacy of the neuromuscular blocking agent rocuronium bromide as a mydriatic agent in European kestrels (Falco tinnunculus) and to assess possible adverse effects due to its use, 10 kestrels received a single topical instillation with a pipette of 0.12 mg of rocuronium in each eye (total dose, 0.24 mg/bird).
A long-acting mydriatic is required in the early stages of treatment in AAU to break down or prevent posterior synechiae and also to reduce pain by immobilising the inflamed iris and ciliary body.