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A motile precursor cell of blood granulocytes found in bone marrow.



one of the types of cells in the hematopoietic tissue of the red bone marrow in vertebrate animals and in man. They are formed from hemocytoblasts and pass through the promyelocyte stage. Granular leukocytes, or granulocytes, develop from myelocytes. The nuclei of myelocytes are round or bean-shaped and less compact than in mature leukocytes; the cytoplasm is weakly basophilic. Myelocytes do not normally enter the bloodstream, but in certain pathological conditions, such as leukemia, they may appear in the blood.

References in periodicals archive ?
Myeloid sarcoma is a mass of immature myeloid cells that is seen more often in children than adults without gender predominance.
Therefore, a high index of suspicion and recognition of immature myeloid cells associated with the reactive cells are required to establish the diagnosis of myeloid sarcoma.
4), we suggest that serum samples from vaccinated persons be tested for neutralization of all DENVs in primary human myeloid cells.
AML is a cancer of the immature myeloid cells or blast cells, which are overproduced and crowd bone marrow.
1]] CML is a type of leukaemia characterized by the increased and unregulated growth of predominantly myeloid cells in the bone marrow and the accumulation of these cells in the blood.
The CCAAT enhancer binding proteins (C/EBPs) are a family of basic leucine zipper transcription factors which participate in the differentiation of several cell types including myeloid cells (Morosetti et al.
METHODS: After exposing HL-60 human myeloid cells to BT, we investigated the cellular effects, including apoptosis, ROS generation, DNA damage, and protein damage.
This t(9;22) translocation results in the formation of the BCR-ABL fusion gene, which codes for a novel protein tyrosine kinase (TK) that is constitutively activated and therefore leads to increased proliferation of myeloid cells, decreased apoptosis and adhesion, and genetic instability of the leukaemic cells.
In this study researchers tested a working model in which free fatty acids (FFA) activated inflammasome dependent IL-1P secretion from myeloid cells, this IL-1P release which then impaired the physiological functions of insulin in insulin target organs.
With the increase of tyrosine kinase activity there is a loss of apoptosis, loss of bone marrow adhesion with an increased release of myeloid cells that leave the bone marrow too soon.