ECMO complications, including disseminated intravascular coagulation (DIC), myocardial stunning
, and neurological complications, were relatively rare in survivors (<10%).
Pediatric myocardial stunning
underscores the cardiac toxicity of conventional hemodialysis treatments.
Conclusively, an uncontrolled activation of calpain has been found to be implicated in the pathophysiology of several cardiovascular disorders  including myocardial IRI , and the inhibition of calpains has been shown to attenuate myocardial stunning
and reduce infarct size after ischemia reperfusion  (Figure 1).
Myocardial hypertrophy is also associated with the decrement in high-energy phosphate levels and the depressed ability of mitochondrial to create energy [7, 8], which results in some extent of myocardial stunning
and apoptosis before surgery .
(1998) Intracoronary shunt insertions presents myocardial stunning
in porcine MIDCAB model.
Prolonged clamp time is associated with myocardial ischemia resulting in myocardial stunning
, although our study did not show an increase in inotrope requirement in patients with prolonged clamp time in the low risk group however the inotrope requirements were more in the high risk group and there was a significant increase in the number of patients requiring peroperative intraaortic balloon pump.
Alternative explanations for this clinical picture are from renal insufficiency, dialysis-induced myocardial stunning
or sepsis-induced cardiomyopathy.
Myocardial ischemia/reperfusion (I/R) injury occurs not only in coronary heart disease but also as a complication of cardiac surgery performed to treat lethal reperfusion injury, myocardial stunning
, reperfusion arrhythmias, and vascular injury.
[sup] The clinical spectrum of myocardial injury after CO poisoning encompasses cardiomyopathy, angina attack, myocardial infarction, arrhythmias, and heart failure up to myocardial stunning
and cardiogenic shock.
* The differential diagnosis for WNV myocarditis includes myocardial stunning
from demand ischemia related to SIRS, Takotsubo cardiomyopathy (stress cardiomyopathy), and Dressler's syndrome.
This ionic disbalance results in myocardial stunning
, myofibrillar hypercontractility, mitochondrial ultrastructural damage and ATP depletion .
This phenomenon is known as "myocardial stunning
." The myocardium recovery time increases with the severity of the ischemia.