nitric oxide synthase

(redirected from NO synthase)
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nitric oxide synthase

[‚nī·trik ¦äk‚sīd ¦sin‚thās]
(biochemistry)
An enzyme that catalyzes the stepwise conversion of the amino acid L-arginine to nitric oxide and L-citrulline. There are three types: the brain (or neuronal) and epithelial nitric oxide synthases, which are always present in cells, and inducible nitric oxide synthase, which is produced as needed.
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Requirement for transcription factor IRF-1 in NO synthase induction in macrophages, Science.
This study leads to the conclusion that bilberry extract may produce an antidepressant-like effect by inhibiting the NO synthase enzyme.
It is produced in endothelial cells by activation of the endothelial NO synthase (eNOS) as a reaction to vascular shear stress (Boo et al.
In addition, many authors have demonstrated that the inhibition of NO synthase, enhanced [E.
Nitric oxide (NO) is a short-lived free radical that influences physiological processes in virtually every tissue and is derived from L-arginine via the action of constitutive NO synthase (NOS) or inducible NO synthase (iNOS), whose activity is induced in several cell types, including human gingival fibroblasts.
Endothelial NO synthase gene polymorphisms and hypertension: a meta-analysis.
Muscular structure, enzyme activity, constitutive and inducible nitric oxide (NO) synthases (endothelial NO oxide synthase [eNOS], neuronal NO synthase [nNOS] and inducible NO synthase [iNOS]), nitrites, nitrates, nitrotyrosine, and the presence of macrophages were analyzed.
There are three different forms of NOS: endothelial NO synthases (e NOS), neuronal NO synthase (nNOS) and inducible NO synthase(iNOS).
Alteration of [beta]-cell constitutive NO synthase activity is involved in the abnormal insulin response to arginine in a new rat model of type 2 diabetes.
Isolated adult rat ventricular myocytes were cultured for 24 hours in a serum- free medium containing either normal (5 mM) or high (25 mM) glucose, in the presence or absence of NO synthase (NOS) inhibitor N[omega]-nitroL-arginine methyl ester (L-NAME, 100 [micro]M), superoxide scavenger superoxide dismutase (SOD, 500U/ml) or peroxy nitrite ([ONOO.