NPC

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NPC

(complexity)

NPC

(architecture)
References in periodicals archive ?
The presentation reports the results of in vitro studies of three PKC activators, bryostatin, DCPLA and diazoxide, on their ability to correct the cholesterol transport defect in NPC1 cells.
The current animal study was aimed at confirming whether NPC1 is essential for Ebola infectivity.
Chandran found as a postdoctoral fellow at the Brigham and Women's Hospital in Boston, MA, turns out to be just such an NPC1 blocker, as described in a separate manuscript by Marceline Cote and co-workers to be published in the same issue of Nature.
In 2011, Chandran, of Albert Einstein College of Medicine in New York City, and others identified NPC1 as Ebola's potential partner in crime (SN Online: 8/24/11).
If it cannot access NPC1, it loses the ability to infect and kill its victims.
The NPC1 protein is embedded within cell membranes, where it helps transport cholesterol within the cell.