NPC

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NPC

(complexity)

NPC

(architecture)
References in periodicals archive ?
The work could lead to a new generation of potential therapies for NPC1 and other similar disorders, as well as neurodegenerative diseases such as Parkinsons and Alzheimers diseases.
The process malfunctions in NPC1 and a number of neurodegenerative diseases, making the AMPK enzyme a potential target for future drugs.
In 2011, Chandran, of Albert Einstein College of Medicine in New York City, and others identified NPC1 as Ebola's potential partner in crime (SN Online: 8/24/11).
If it cannot access NPC1, it loses the ability to infect and kill its victims.
To confirm their finding that NPC1 is crucial for Ebola virus infection, the researchers challenged mice carrying a mutation in NPC1 with Ebola virus.
At 50% stress level, there was practically no increase for the FRC10S and FRC30S while there was a slight increase for NPC1 and FRC12M compared to 30 % stress level, the increment could be due to the testing variation.
There are several types of Niemann-Pick disease; this study focused on mice that had been bred with a faulty NPC1 gene to model Niemann-Pick disease, type C1.
Previous studies in mice have suggested that this gene has a role in controlling appetite, as mice with a non-functioning NPC1 gene suffer late-onset weight loss and have poor food intake.