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nitroglycerin (nīˌtrōglĭsˈərĭn), C3H5N3O9, colorless, oily, highly explosive liquid. It is the nitric acid triester of glycerol and is more correctly called glycerol trinitrate. It is insoluble in water but soluble in ether, acetone, benzene, and chloroform. An unstable compound, nitroglycerin decomposes with explosive violence when heated or jarred. It is mixed with an absorbent material to form dynamite (which is not so sensitive to slight shocks) and is also used as a component of smokeless powder. Nitroglycerin was discovered (c.1847) by the Italian chemist Ascanio Sobrero and was first produced commercially by Alfred Nobel. It is used medicinally to provide temporary relief from the symptoms of angina pectoris; the body converts it to nitric oxide, which causes narrowed blood vessels to relax.
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The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



(glyceryl trinitrate), ONO2CH2—CHO-NO2—CH2ONO2, the triester of glycerol with nitric acid; a powerful explosive.

Nitroglycerin is an oily, colorless liquid that crystallizes in two modifications: a labile form (melting point, 2.8°C) and a stable form (melting point, 13.5°C). Density, 1.591 g/cm3 (25°C). Nitroglycerin is virtually insoluble in water but readily soluble in acetone, ether, and benzene. It explodes upon even a slight impact. Heat of explosion, 6.3 megajoules per kg, or 1,500 kcal/kg; detonation rate, 7.7 km/sec; volume of gaseous explosion products, 713 liters per kg; flash point, ∼200°C.

Nitroglycerin is produced by nitration of glycerol with a nitrating mixture. It is used in significant quantities as a secondary explosive in the production of dynamites and various propellants.

Nitroglycerin produces dilation of the cardiac blood vessels; it is used in medical practice in the form of an ethanol solution (in drops) and in tablets to relieve attacks of angina pectoris.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.


(organic chemistry)
CH2NO3CHNO3CH2NO3 Highly unstable, explosive, flammable pale-yellow liquid; soluble in alcohol; freezes at 13°C and explodes at 260°C; used as an explosive, to make dynamite, and in medicine. Also spelled nitroglycerine.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.


, nitroglycerin
a pale yellow viscous explosive liquid substance made from glycerol and nitric and sulphuric acids and used in explosives and in medicine as a vasodilator. Formula: CH2NO3CHNO3CH2NO3
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005
References in periodicals archive ?
Nasdaq has informed NeuroSearch also that it will begin a process to evaluate whether the shares of NeuroSearch may continue to be admitted to trading, unless in all material respects NeuroSearch adheres to the model for a combination with NTG in accordance with the timetable referred to above.
As shown in Figure 3A, the erythrocyte numbers in the NTG and TG were 6.02 to 6.66x[10.sup.6]/[micro]L and 6.15 to 6.53x[10.sup.6]/[micro]L, respectively during the experiment.
Harris Williams was financial advisor, and Evershed Sutherland LLP was legal advisor to NTG. Sheppard Mullin acted as TI and Gryphon's legal advisor, while North Inlet served as financial advisor.
NTG's balance sheet strength assessment has shown a material improvement during 2017.
Subjects who met all of the following criteria were included: untreated NTG with normal and open anterior chamber angles on slit-lamp biomicroscopy and gonioscopy, an ONH that appeared to be glaucomatous on stereoscopic evaluation with a corresponding visual field defect, IOP < 21 mmHg throughout 1 day (measured every 3 hours) or on at least three separate days, a spherical refractive error between -8.00 and +4.00 diopters (D), a cylindrical refractive error within 2.5 D, and best-corrected visual acuity of at least 20/25.
Although BNP levels were decreased in both groups, the amount of decrease in BNP level was higher in the NTG group than that in the ST group (80% of initial level in IV NTG group and 50% of initial level in the ST group, p<0.001).
As shown in Figure 2, HFD consumption induced glucose intolerance in both groups, although the effect of the HFD was more potent in the apoCIII mice (Figure 2(a)), which showed a 12% increase in the area under the glycemic curve compared to the NTg group.
NTG produces hyperalgesia in rats through the activation of spinal and brainstem structures which contribute to nociception [8].
This study aims to analyze serum total oxidant and antioxidant potentials in NTG and PEXG patients separately.
METHODS: In this prospective, randomized, controlled, open study, efficacy of NTG sublingual spray on haemodynamic response to tracheal extubation was evaluated in sixty patients, between 20-60 years of age and of American Society of Anesthesiologists (ASA) physical status class 1-2, scheduled for Elective lumbar disc surgery after Institutional Ethics Committee approval.
It includes a 10-year epidemiology forecast of total prevalent cases of glaucoma segmented by age (in five-year increments beginning at age 40), sex, clinical type (POAG, PACG, secondary glaucoma, and congenital glaucoma the total prevalent cases of NTG, which is a sub-type of OAG; and the diagnosed prevalent cases of POAG and PACG in these markets.
Mohamed Al-Ballaa, Chairman of Mubasher Financial Services and Executive Chairman of NTG,was honoured with a prestigious award at the 23 rd session of the Arab Economic Forum (AEF).