nitroglycerin

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nitroglycerin

(nī'trōglĭs`ərĭn), C₃H₅N₃O₉, colorless, oily, highly explosive liquid. It is the nitric acid triester of glycerolglycerol,
glycerin,
glycerine,
or 1,2,3-propanetriol
, CH₂OHCHOHCH₂OH, colorless, odorless, sweet-tasting, syrupy liquid. Glycerol is a trihydric alcohol. It melts at 17.
..... Click the link for more information. and is more correctly called glycerol trinitrate. It is insoluble in water but soluble in ether, acetone, benzene, and chloroform. An unstable compound, nitroglycerin decomposes with explosive violence when heated or jarred. It is mixed with an absorbent material to form dynamitedynamite,
explosive made from nitroglycerin and an inert, porous filler such as wood pulp, sawdust, kieselguhr, or some other absorbent material. The proportions vary in different kinds of dynamite; often ammonium nitrate or sodium nitrate is added.
..... Click the link for more information. (which is not so sensitive to slight shocks) and is also used as a component of smokeless powder. Nitroglycerin was discovered (c.1847) by the Italian chemist Ascanio Sobrero and was first produced commercially by Alfred NobelNobel, Alfred Bernhard
, 1833–96, Swedish chemist and inventor. Educated in St. Petersburg, Russia, he traveled as a youth and returned to St. Petersburg in 1852 to assist his father in the development of torpedoes and mines.
..... Click the link for more information. . It is used medicinally to provide temporary relief from the symptoms of angina pectorisangina pectoris
, condition characterized by chest pain that occurs when the muscles of the heart receive an insufficient supply of oxygen. This results when the arteries that supply the heart muscle with oxygenated blood are narrowed by arteriosclerosis.
..... Click the link for more information. ; the body converts it to nitric oxide, which causes narrowed blood vessels to relax.

The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Nitroglycerin

(glyceryl trinitrate), ONO₂CH₂—CHO-NO₂—CH₂ONO₂, the triester of glycerol with nitric acid; a powerful explosive.

Nitroglycerin is an oily, colorless liquid that crystallizes in two modifications: a labile form (melting point, 2.8°C) and a stable form (melting point, 13.5°C). Density, 1.591 g/cm³ (25°C). Nitroglycerin is virtually insoluble in water but readily soluble in acetone, ether, and benzene. It explodes upon even a slight impact. Heat of explosion, 6.3 megajoules per kg, or 1,500 kcal/kg; detonation rate, 7.7 km/sec; volume of gaseous explosion products, 713 liters per kg; flash point, ∼200°C.

Nitroglycerin is produced by nitration of glycerol with a nitrating mixture. It is used in significant quantities as a secondary explosive in the production of dynamites and various propellants.

Nitroglycerin produces dilation of the cardiac blood vessels; it is used in medical practice in the form of an ethanol solution (in drops) and in tablets to relieve attacks of angina pectoris.

nitroglycerin

[¦nī·trə′glis·ə·rən]

(organic chemistry)

CH₂NO₃CHNO₃CH₂NO₃ Highly unstable, explosive, flammable pale-yellow liquid; soluble in alcohol; freezes at 13°C and explodes at 260°C; used as an explosive, to make dynamite, and in medicine. Also spelled nitroglycerine.

nitroglycerine

, nitroglycerin

a pale yellow viscous explosive liquid substance made from glycerol and nitric and sulphuric acids and used in explosives and in medicine as a vasodilator. Formula: CH₂NO₃CHNO₃CH₂NO₃

Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005

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Effects of transport stress on physiological responses and milk production in lactating dairy cows

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Although BNP levels were decreased in both groups, the amount of decrease in BNP level was higher in the NTG group than that in the ST group (80% of initial level in IV NTG group and 50% of initial level in the ST group, p<0.001).

Effect of intravenous nitrate treatment on serum BNP level and 30-day follow-up events in decompensated systolic heart failure

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Apolipoprotein CIII Overexpression-Induced Hypertriglyceridemia Increases Nonalcoholic Fatty Liver Disease in Association with Inflammation and Cell Death

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Higher serum lipids and oxidative stress in patients with normal tension glaucoma, but not pseudoexfoliative glaucoma

METHODS: In this prospective, randomized, controlled, open study, efficacy of NTG sublingual spray on haemodynamic response to tracheal extubation was evaluated in sixty patients, between 20-60 years of age and of American Society of Anesthesiologists (ASA) physical status class 1-2, scheduled for Elective lumbar disc surgery after Institutional Ethics Committee approval.

The effects of nitroglycerine (NTG) sublingual spray to blunt the haemodynamic response to endotracheal extubation in lumbar disc surgery

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"EpiCast Report: Glaucoma - Epidemiology Forecast to 2023" now available at Fast Market Research

Mohamed Al-Ballaa, Chairman of Mubasher Financial Services and Executive Chairman of NTG,was honoured with a prestigious award at the 23 rd session of the Arab Economic Forum (AEF).

Mubasher Financial Services' chairman honoured at AEF's 23rd session

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