naltrexone

(redirected from Naltrexone hydrochloride)
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naltrexone

[nal′trek‚zōn]
(pharmacology)
C20H23NO4 An opiate receptor antagonist that blocks the effects of endogenous opioids in the brain; used to treat alcoholism.
References in periodicals archive ?
According to the results in Table 4, administration of naltrexone hydrochloride in pregnant rats via intraperitoneal in prenatal period, promoted a 25% reduction in total length of seminiferous tubules and 20% of the Sertoli cells population compared to control animals.
EMBEDA([R]) is an extended-release oral formulation of morphine sulfate and naltrexone hydrochloride indicated for the management of moderate to severe pain when a continuous, around-the-clock opioid analgesic is needed for an extended period of time.
This study was designed to determine the optimal ratio of oxycodone hydrochloride and the opioid antagonist, naltrexone hydrochloride, to significantly block the euphoric effect of the opioid if the product is abused by physically altering it by crushing.
This study was designed to determine the optimal ratio of oxycodone hydrochloride and opioid antagonist, naltrexone hydrochloride, to significantly block the euphoric effect of the opioid if the product is abused.
Specialist pharmaceutical company Elite Pharmaceuticals Inc (OTCBB:ELTP) revealed on Wednesday the completion of the acquisition of a currently approved Abbreviated New Drug Application (ANDA) for naltrexone hydrochloride (50 mg tablets) from Mikah Pharma LLC (Mikah).
ELI-216 is a controlled-release oxycodone hydrochloride agonist combined with an opioid antagonist, naltrexone hydrochloride, formulated to deter abuse of the drug.
The study is designed to evaluate the euphoria blocking effects of ELI-216 and to determine the appropriate levels of naltrexone hydrochloride required to reduce or eliminate the euphoria experienced by abusers of oxycodone hydrochloride.