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Related to Necrobiosis: necrobiosis lipoidica diabeticorum


Death of a cell or group of cells under either normal or pathologic conditions.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



the change that occurs in a cell prior to cell death. Necrobiosis is linked with metabolic disturbances that may lead to fatty degeneration or to other types of degeneration in the cell. These degenerative changes can be reversible. The most typical symptoms of necrobiosis are changes in the cell nucleus, such as karyopyknosis, karyorrhexis, and karyolysis; disturbances in the viscosity of the cytoplasm; an abnormal staining reaction; and disorganization of the enzyme systems of the cell, which leads to cellular autolysis.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Barnes, "Necrobiosis lipoidica: Only a minority of patients have diabetes mellitus," British Journal of Dermatology, vol.
Some of the cutaneous markers of diabetes mellitus like necrobiosis lipoidica diabeticorum, diabetic bullae, acquired perforating dermatosis and stiff skin syndrome is not seen in our study.
Variable histologic findings in postherpetic eruptions include presence of eosinophils or plasma cells within the infiltrate, palisading, necrobiosis, elastosis, elastophagocytosis, interstitial mucin, and lymphocytic cuffing" of histiocyte aggregates in a tuberculoid fashion.
necrobiosis lipoidica, a progressive condition normally associated with diabetics, five years ago.
Necrobiosis appears as one or more shiny, atrophic plaques with visible underlying blood vessels.
The differential diagnosis also needs to exclude rheumatoid nodules, necrobiosis lipoidica diabeticorum, and lichen planus.
A differential diagnosis for infections should include necrobiosis lipoidica, noted Dr.
"I suffer from a condition called necrobiosis, caused by changes in cells of the skin, and it is normally associated with people who have diabetes - which I don't have.
QI AM a diabetic on insulin, of which I take 76 units a day, and I have a skin disease called Necrobiosis Lipoidica Diabeticorum.