neoadjuvant chemotherapy

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neoadjuvant chemotherapy

[‚nē·ō¦aj·ə·vənt ‚kē·mō′ther·ə·pē]
(medicine)
A type of chemotherapy that is used to shrink a tumor prior to surgery or radiation.
References in periodicals archive ?
The Paradigm Neoadjuvant Breast Registry will use Paradigm's PCDx next generation sequencing test and other advanced molecular capabilities to genomically characterize invasive breast cancer patients for targeted neoadjuvant therapies[pre-surgical treatment].
A retrospective cohort study of 236 patients with clinical stage [greater than or equal to] T2 bladder cancer between 2002 and 2004 treated with radical cystectomy in Edmonton evaluated the rate of referral to medical oncology for consideration of neoadjuvant chemotherapy (NACT).
Neoadjuvant chemotherapy for osteogenic sarcoma: A five year follow-up (T-10) and preliminary report of new studies (T-12).
The study compared the combination of Perjeta, Herceptin and docetaxel chemotherapy with placebo, Herceptin and chemotherapy in 808 people with previously untreated HER2-positive mBC, or with HER2-positive mBC that had come back after prior therapy in the adjuvant or neoadjuvant setting.
Neoadjuvant therapy for locally advanced breast cancer: Focus on chemotherapy and biological targeted treatments' armamentarium.
Related to histologic grade and proliferative activity are molecular subtypes of breast cancer, which are increasingly used for prediction of neoadjuvant response.
However, if researchers can identify the biochemical pathway that controls Par-4, or molecules that can modulate Par-4 activity directly, they may be able to increase the efficacy of neoadjuvant therapy of primary tumors as well as treat recurrent breast cancers more effectively, Alvarez said.
3) presented a patient with bladder carcinosarcoma who achieved a complete response after neoadjuvant radiochemotherapy.
ORLANDO - Neoadjuvant chemotherapy with interval debulking surgery yields similar overall and longer progression-free survival when compared with primary debulking surgery for women with stage IV epithelial ovarian cancer, according to a retrospective study.
Further advantages of early diagnosis of large-volume axillary disease include aiding decision-making for neoadjuvant chemotherapy or for post-mastectomy radiotherapy, which impacts on the outcome of definitive immediate breast reconstruction.
Neoadjuvant paclitaxel, ifosfamide, and cisplatin chemotherapy for metastatic penile cancer: A phase II study.
Overall, these results suggest that metformin would reduce the local production of estrogens within the breast thereby providing a new key therapeutic tool that could be used in the neoadjuvant and adjuvant settings and conceivably also as a preventative measure in obese women.