hyperplasia

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hyperplasia

(hī'pərplā`zhə): see hypertrophyhypertrophy
, enlargement of a tissue or organ of the body resulting from an increase in the size of its cells. Such growth accompanies an increase in the functioning of the tissue. In normal physiology the growth in size of muscles (e.g.
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.

Hyperplasia

 

an increase in the number of structural elements of tissues or organs. In man and animals, hyperplasia is based on the intensified reproduction of cells and the formation of new structures. Hyperplasia is observed in various types of pathological growth of tissues (chronic productive inflammation and tumor), in regeneration, and in hypertrophy. Hyperplasia often carries with it compensating characters. In plants, it may be a local growth of tissues resulting from mitotic or amitotic cell division. It occurs with infection by destructive or pathogenic organisms, during trauma, and under the influence of growth stimulants, pesticides, and other preparations. The result of hyperplasia is the formation of galls, calluses, and warts.

hyperplasia

[‚hī·pər′plā·zhə]
(medicine)
Increase in cell number causing an increase in the size of a tissue or organ.
References in periodicals archive ?
sup][7] Therefore, accelerating re-endothelialization of injured vessels is important for recovery of vascular function, prevention of thrombosis, and inhibition of excessive neointimal hyperplasia.
In conclusion, transplantation of EPCs derived from human early fetal aortas may inhibit neointimal hyperplasia of damaged vessels.
ZA treatment significantly decreased the neointimal hyperplasia (39.
In the present study, we demonstrated that the injury by carotid artery anastomosis induces intensive neointimal hyperplasia, and increased intima/media index and [alpha]-smooth muscle actin immunopositivity in rabbits from placebo (PBS) group.
The purpose of this study was to compare the effects of ticlopidine and clopidogrel on the development of neointimal hyperplasia and PDGF and b-FGF, which have a significant role in SMC proliferation and migration following experimental arterial injury.
10) demonstrated that clopidogrel significantly reduced the development of neointimal hyperplasia in an experimental model, which is similar with the one we used in our study.
Following the second injury that occurred after balloon dilation, further remodeling of the carotid artery was evident with acute luminal dilatation, plaque fracture and extensive neointimal hyperplasia, reproducing the results of balloon angioplasty in human diseased vessels.
Notably, mild VV neovascularization and neointimal hyperplasia were detected in carotid arteries following primary injury.
1% in the highest dose arm due to paclitaxel's cytostatic mechanism of action in inhibiting neointimal hyperplasia.
Previous clinical studies have shown that paclitaxel-coated stents dramatically inhibited neointimal hyperplasia, as evidenced by angiography and IVUS evaluations at six months.
Paclitaxel-coated stents produced a dramatic inhibition of neointimal hyperplasia, as evidenced by angiography and IVUS evaluations at six months, according to ASPECT study results.
Paclitaxel's cytostatic mechanism of action results in dramatic inhibition of neointimal hyperplasia, as evidenced by angiographic and IVUS evaluations at six months, according to ASPECT study results.