hyperplasia

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hyperplasia

(hī'pərplā`zhə): see hypertrophyhypertrophy
, enlargement of a tissue or organ of the body resulting from an increase in the size of its cells. Such growth accompanies an increase in the functioning of the tissue. In normal physiology the growth in size of muscles (e.g.
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.

Hyperplasia

 

an increase in the number of structural elements of tissues or organs. In man and animals, hyperplasia is based on the intensified reproduction of cells and the formation of new structures. Hyperplasia is observed in various types of pathological growth of tissues (chronic productive inflammation and tumor), in regeneration, and in hypertrophy. Hyperplasia often carries with it compensating characters. In plants, it may be a local growth of tissues resulting from mitotic or amitotic cell division. It occurs with infection by destructive or pathogenic organisms, during trauma, and under the influence of growth stimulants, pesticides, and other preparations. The result of hyperplasia is the formation of galls, calluses, and warts.

hyperplasia

[‚hī·pər′plā·zhə]
(medicine)
Increase in cell number causing an increase in the size of a tissue or organ.
References in periodicals archive ?
10) demonstrated that clopidogrel significantly reduced the development of neointimal hyperplasia in an experimental model, which is similar with the one we used in our study.
2010 JVIR Editor's Award for Outstanding Laboratory Investigation: "Hypoxia-induced Phenotypic Switch of Fibroblasts to Myofibroblasts Through a Matrix Metalloproteinase 2/tissue Inhibitor of Metalloproteinase-mediated Pathway: Implications for Venous Neointimal Hyperplasia in Hemodialysis Access," S.
Because the pre-clinical data demonstrate lower neointimal hyperplasia and improved endothelial coverage, we look forward to obtaining clinical confirmation of the results.
Phase 1/2 Clinical Study Will Evaluate Safety and Efficacy of SB-030 in the Reduction of Short-Term Neointimal Hyperplasia Following Vascular Intervention-
Importantly, the data also showed minimal neointimal hyperplasia (NIH) formation.
Previously reported imaging studies have revealed high rates of initial healing after implantation of the MiStent SES with early stent strut coverage, normal endothelial function at nine months combined with a minimal progression of neointimal hyperplasia through 18 months.
Factors involved in restenosis include early vascular recoil, negative vascular remodeling, and neointimal hyperplasia [3, 4, 5, 6].
Previous studies have shown that the main cause of LSM was positive remodeling without an equal amount of peristent neointimal hyperplasia or plaque growth so that the vessel pulled away from the stent without tissue fill-in; thrombus resolution so that a gap formed between the stent and the vessel wall was a potential mechanism after primary stenting in acute myocardial infarction (AMI) (4, 5).
Attempts to retract or remove the bare metal Wallstent (Boston Scientific, Natick, MA) may be confounded by the inability to separate the metallic shunt from the vein due to neointimal hyperplasia between the interstices of the bare metal stent and scar tissue formation from the braided metal moving and irritating the vein wall.
A common complication of heart bypass is neointimal hyperplasia, which is the blood vessel's response to injury.