and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term.
(CN) is an uncommon, benign cystic neoplasm of the kidney, composed of epithelial and stromal elements; CN typically develops in adults older than 30 years with a strong female sex predilection.
Genetic diversity of green algal and cyanobactcrial photobionts in Nephroma
Multilocular cystic nephroma
(MLCN) findings are well-defined multiple cysts separated by echogenic septa.
Congenital mesoblastic nephroma
(leiomyomatous hamartoma): first adult case.
World Health Organization (WHO) histological classification of benign renal neoplasms Renal cell tumors Metanephric tumors Mesenchymal tumors Oncocytoma Metanephric adenoma Angiomyolipoma Papillary adenoma Metanephric adenofibroma Leiomyoma Metanephric stromal tumor Hemangioma Lymphangioma Reninoma Fibroma Schwannoma Renal cell tumors Mixed epithelial mesenchymal tumors Oncocytoma Cystic nephroma
Papillary adenoma Mixed epithelial and stromal tumor
The differential diagnosis of a renal neoplasm ranges from more common entities, including neuroblastoma, nephroma
and Wilms' tumour, to less frequent ones, such as renal cell carcinoma, and rare entities, such as ossifying renal tumour of infancy (ORTI).
42) The differential diagnoses mainly include cystic nephroma
, benign multilocular renal cortical cysts, and clear cell papillary carcinoma with predominant cystic configuration.
A rare benign cystic lesion, the multilocular cystic nephroma
(MLCN) presents as a mass lesion with multiple internal cysts.
4] Carpenter and colleagues demonstrated breakpoints in the q13-15 region of chromosome 12 in leiomyomas and congenital mesoblastic nephroma
Microscopically, multilocular cystic nephroma
demonstrates multilocular cysts lined by a single layer of flattened, low, cuboidal epithelium with eosinophilic cytoplasm and no nuclear atypia.
Congenital fibrosarcoma is another spindle cell sarcoma associated with a characteristic cytogenetic change, the t(12;15)(p13;q26) translocation, not found in adult fibrosarcomas or other sarcomas (123,124) and identical to that described for congenital mesoblastic nephroma