Conclusion: The results of our study concluded that level of serum uric acid and microalbuminuria are significantly correlated to
nephropathy in patients having Type-2 diabetes mellitus.
Glycosylation of tissue proteins may contribute to diabetic
nephropathy apart from other microvascular complications.
During the Phase 2 clinical trial, all patients with IgA
nephropathy demonstrated clinically meaningful improvement in proteinuria.
Nephropathy - Products under Development by Companies 12
Renal phospholipase A2 receptor staining in patients with idiopathic membranous
nephropathyinitiated Phase III clinical trial of its investigational compound atrasentan for treatment of diabetic
nephropathy.
In contrast, in Australia, France, Finland, Italy and Czech Republic; IgA
nephropathy is the most common primary glomerular disease according to Fiorentino et al13.
They believe the risk for heat stress
nephropathy has increased due to global warming and an increase in extreme heat waves, and it is having a disproportionate impact on vulnerable populations, such as agricultural workers.
Diabetic
nephropathy is the most common cause of End Stage Renal Disease (ESRD).
Conclusion: Diabetes mellitus, heart failure, chronic kidney disease, advanced age and higher contrast dose were significantly associated with contrast induced
nephropathy.
Being a developing country with low resources, it is the dire necessity that studies be conducted to find the comparative efficacy of these drugs in prevention of microalbuminuria and diabetic
nephropathy, so that an effective and affordable approach could be adopted.
Diabetic rats were divided into two groups; the islets group received islets transplantation under the kidney capsule; and the diabetic
nephropathy (DN) group consisted of untreated diabetic
nephropathy rats.
