neural cell adhesion molecule

(redirected from Neural cell adhesion molecules)

neural cell adhesion molecule

[¦nu̇r·əl ‚sel ad′hē·zhen ‚mäl·ə‚kyül]
(neuroscience)
A calcium-independent cell adhesion molecule expressed by migrating neurons that mediates intercellular binding via homophilic mechanisms (by binding to other neural cell adhesion molecules); important in neuronal aggregation.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Polysialylated neural cell adhesion molecules expressed in human pituitary tumors and related to extrasellar invasion.
Expression and secretion of neural cell adhesion molecules by human pituitary adenomas.
Currently, there are few reports in the literature regarding the role of cell adhesion proteins, such as E-cadherin (ECAD), and neural cell adhesion molecule (NCAM) in pituitary adenomas, as well as of SLUG, which is an important transcriptional regulator of ECAD.
Differential expression of the neural cell adhesion molecule NCAM 140 in human pituitary tumors.
Schachner, "Neural cell adhesion molecules of the immunoglobulin superfamily regulate synapse formation, maintenance, and function," Trends in Neurosciences, vol.
Neural cell adhesion molecule 1 (NCAM1; see Figure 1 for a comparison of the structure of this CAM to other CAMs discussed in subsequent sections) is expressed across many cell types, including neurons, glial cells, cardiac muscle cells, and skeletal muscle cells, with as many as 27 distinct isoforms generated by alternative RNA splicing [15].
Doherty, "Structure and function of the gene for neural cell adhesion molecule," Seminars in Neuroscience, vol.
White et al., "Chemical characterization of a neural cell adhesion molecule purified from embryonic brain membranes," The Journal of Biological Chemistry, vol.
Correlation of neural cell adhesion molecules with perineural spread of squamous cell carcinoma of the head and neck.
Neural cell adhesion molecules are important both for their role they play in the genesis and maintenance of synaptic connections, and therefore the understanding of neurological disorders and psychiatric conditions, and for their postulated role in the evolution of the human brain.
The other topics are polyunsaturated fatty acid deficiency, the correlation between vascular endothelial growth factor and proto-oncogene c-fos and c-myc, and the expression of neural cell adhesion molecules and osteonectin.