Neuroblastoma


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neuroblastoma

[‚nu̇r·ō·bla′stō·mə]
(medicine)
A malignant neoplasm composed of anaplastic sympathicoblasts; occurs usually in the adrenal medulla of children.

Neuroblastoma

 

a malignant tumor of nerve tissues, occurring most frequently in children. Classified as neuroblastomas are sympathicogoniomas, sympathicoblastomas, and ganglioblastomas. In most cases, neuroblastomas originate in the medulla glandulae suprarenalis, in the sympathetic trunk, and in the pelvic and abdominal divisions of the sympathetic nervous system.

References in periodicals archive ?
During Childhood Cancer Awareness Month in September, Neuroblastoma UK will be encouraging people to join them in #GoingGold by wearing a Gold Ribbon, an awareness symbol to show support for children with cancer and their families.To find out how to support Neuroblastoma UK this September, visit www.neuroblastoma.org.uk/childhood-cancer-awareness-month
Neuroblastoma UK is a national charity dedicated to finding a cure for neuroblastoma, a rare childhood cancer.
Archie Wilks, from Saffron Walden, Essex, was diagnosed with neuroblastoma in January, just weeks after he became unwell and was unable to stand.
Neuroblastoma is a cancer often found in the small glands on top of the kidneys (adrenal glands).
Treatment strategies of high-risk neuroblastoma are guided by the Children's Oncology Group (COG) based on age, International Neuroblastoma Staging System (INSS) stage, and tumor biology notably International Neuroblastoma Pathology Classification system (INPC), amplication of N-myc proto-oncogene and DNA ploidy.
Claire added: "There are two clinical trials coming up for neuroblastoma to stop it coming back and they are both in America.
The second commonest solid tumor in children is neuroblastoma, It originates from neuroepithelial cells that migrate from neural crest and form sympathetic nervous system.1 Mostly (70%) arising retroperitoneally and involve adrenal medulla and may invade surrounding tissues or have distant metastasis in lymph nodes, liver, bone marrow, orbit, skull, ovaries, paratesticular region, testis and central nervous system.2
Over a median follow-up of 13.3 years, the researchers found that neuroblastoma survivors had an increased prevalence of impairment in the domains of anxiety/depression, headstrong behavior, attention deficits, peer conflict/social withdrawal, and antisocial behavior, compared to siblings.
Frozen section of these nodes was consistent with a diagnosis of neuroblastoma. The incision was closed in the standard fashion and a suction drain left in place.
The university leads a national genetics reference scheme with the Northern Genetics Service, receiving neuroblastomas at diagnosis and relapse from nearly all children in the UK to carry out detailed genetic testing on tumours to determine what type of neuroblastoma a patient has.
Neuroblastoma (NB) is the most common extracranial solid tumor in children, accounting for 7% of all pediatric neoplasms in patients under 15 years and 15% of all pediatric deaths caused by cancers.