Presenting their research at the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting, researchers are not sure why spontaneous and unexplained disturbance in REM sleep should lead to a
neurodegenerative disease like Parkinson's, but new longitudinal imaging data show a clear correlation between idiopathic REM behavior disorder and dysfunction of the dopamine transporter system involved in a wide range of vital brain functions, including memory and motor control.
This report and its recommendations are based on the conference "Early Environmental Origins of
Neurodegenerative Disease in Later Life: Research and Risk Assessment" sponsored by the Mount Sinai Center for Children's Health and the Environment.
Appel, a renowned and recognized global leader in neuromuscular and
neurodegenerative disease research, has been working in concert with Dr.
A half dozen or so
neurodegenerative diseases stem from an excess of CAG repeats.
Highlights include the perspective by David Schubert and Pamela Maher of the Salk Institute for Biological Studies (CA, USA) that considers a different approach to drug discovery in this disease area, highlighting the fact that there are currently no drugs that halt the progression of any age-associated
neurodegenerative disease.
The Global
Neurodegenerative Diseases Market 2015-2019 research report says reformulation of marketed drugs is boosting the growth of
neurodegenerative diseases market during the period reviewed for forecasts in this research.
Led by researchers from the Research Institute of the MUHC, the Universite de Montreal and the Hopital du Sacre-CA[pounds sterling]ur de Montreal, the study showed that the chance that a a patient with an REM sleep behaviour disorder would develop a
neurodegenerative disease was 17.
Precise determinations of
neurodegenerative disease can be elusive, although for approximately 80% of cases, a diagnosis made by a clinician is confirmed postmortem (Mok et al.
To determine whether the mutant mRNAs were specific to ALS, Rothstein's group examined brain and spinal cord tissue from 24 people who had died of other
neurodegenerative diseases or non-neurological causes.
Table 30:
Neurodegenerative Disease Market, Alzheimer's Disease, Revenue by Country ($m), 2002-2010 38
Elixir will own the rights to the new compounds for use in all disease areas, excluding
neurodegenerative diseases, for which Siena Biotech will have the right to obtain an exclusive license.
AD/PD(TM) is now the world's foremost platform devoted to promoting the latest advances in
neurodegenerative disease research and new therapies.