neurodegenerative

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neurodegenerative

[‚nu̇·rō·di′jen·rəd·iv]
(pathology)
Characterized by the gradual and progressive loss of nerve cells.
References in periodicals archive ?
NFTs, which are made up of aggregated tau protein, are a hallmark of several neurodegenerative diseases, including Alzheimer's disease.
In an effort to examine the impact of receiving metformin treatment on the incidence of neurodegenerative disease and the association between length of metformin exposure and the risk of neurodegenerative diseases, the researchers used the Veterans Affairs database from 2004 to 2010 to study 6,046 patients who were at least 50 years of age with type 2 diabetes mellitus and were receiving long-term insulin treatment.
Neurodegenerative Disease Market: Drivers & Restraints
NESS ZION A, Israel, August 4, 2014 -- Israeli biotechnology company Kadimastem (TASE: KDST) reports that it has signed a collaboration agreement with Merck to carry out drug screening in the neurodegenerative diseases space for multiple sclerosis (MS), and potential other neurodegenerative diseases.
Presenting their research at the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting, researchers are not sure why spontaneous and unexplained disturbance in REM sleep should lead to a neurodegenerative disease like Parkinson's, but new longitudinal imaging data show a clear correlation between idiopathic REM behavior disorder and dysfunction of the dopamine transporter system involved in a wide range of vital brain functions, including memory and motor control.
This report and its recommendations are based on the conference "Early Environmental Origins of Neurodegenerative Disease in Later Life: Research and Risk Assessment" sponsored by the Mount Sinai Center for Children's Health and the Environment.
Appel, a renowned and recognized global leader in neuromuscular and neurodegenerative disease research, has been working in concert with Dr.
A half dozen or so neurodegenerative diseases stem from an excess of CAG repeats.
Highlights include the perspective by David Schubert and Pamela Maher of the Salk Institute for Biological Studies (CA, USA) that considers a different approach to drug discovery in this disease area, highlighting the fact that there are currently no drugs that halt the progression of any age-associated neurodegenerative disease.
TSX: 4502) and South San Francisco, California-based neurodegenerative disease therapeutic-focused Denali Therapeutics (NASDAQ: DNLI) have entered into a strategic option and collaboration agreement to develop and commercialize up to three specified therapeutic product candidates for neurodegenerative diseases, the company said.
The researchers tested their hypothesis regarding a series of neurodegenerative diseases that includes Alzheimers and found that a decrease of the SIRT6 protein results in increased DNA damage and preceded other markers of encroaching disease such as hyperphosphorylated Tau.
Many neurodegenerative diseases arise when glial cells are damaged or destroyed, causing neurons to malfunction and eventually die.