Neurofibroma


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neurofibroma

[¦nu̇r·ō·fī′brō·mə]
(medicine)
A tumor characterized by the diffuse proliferation of peripheral nerve elements. Also known as endoneural fibroma; myxofibroma of nerve sheath; neurofibromyxoma; perineural fibroblastoma; perineural fibroma.

Neurofibroma

 

a benign tumor that originates in membranes of peripheral nerves and is localized in any part of the body along the path of a nerve trunk. Neurofibromas most often affect the sciatic and intercostal nerves. The multiple occurrence of neurofibromas is called neurofibromatosis.

References in periodicals archive ?
3) While patients with segmental NF may exhibit some of these same findings, the distribution of neurofibromas is often limited to one dermatome.
Medallion-like dermal dendrocyte hamartoma: a case misdiagnosed as neurofibroma.
Solitary Plexiform Neurofibroma of the Gingiva: Unique Presentation in the Oral Cavity.
In our case, involvement of sacroiliac joint was secondary to juxtaarticular plexiform neurofibroma with massive invasion of the right sacroiliac joint.
Bajo anestesia general se realizo la diseccion hasta la aponeurosis cervical profunda con diseccion del paquete vasculonervioso cervical (arteria carotida, vena yugular interna y nervio neumogastrico), logrando la reseccion del neurofibroma, tumor solido de consistencia dura, forma ovalada y sin abundante vascularizacion (figura 3).
Abstract: Peripheral nerve sheath tumors are a heterogeneous group of neoplasms that comprise neurofibromas, schwannomas, neurilemmomas, and perineuromas.
Lesions like bronchogenic cyst and neurofibroma were suspected by CT imaging, but surgical excision proved to be both diagnostic and therapeutic.
Neurofibroma lacks capsule, rich in mucopolysaccharide ground substance and has fewer axons.
An incision biopsy from the posterior mandibular lesion which microscopically revealed interlacing bundles of spindle shaped cells with wavy nuclei, delicate collagen fibres, plump fibroblasts, and a strong positive reaction with S-100 (detection system, HRP polymer) confirmed the diagnosis of simple neurofibroma (Figures 2(a) and 2(b)).
18-FDG-PET-CT scan helps in differentiating MPNST from benign neurofibroma in NF-1 patients and detecting malignant transformation of benign plexiform neurofibromas [1, 3].
The schwanoma and neurofibroma differ histologically and histogenetically; the schwannoma is derived from the Schwann cells and the neurofibroma from the fibroblasts of the perineurium.
Pigmented neurofibroma can be differentiated from Bednar tumour by more extensive storiform growth and strong positivity for CD34 in latter.