3) While patients with segmental NF may exhibit some of these same findings, the distribution of
neurofibromas is often limited to one dermatome.
Medallion-like dermal dendrocyte hamartoma: a case misdiagnosed as
neurofibroma.
Solitary Plexiform
Neurofibroma of the Gingiva: Unique Presentation in the Oral Cavity.
In our case, involvement of sacroiliac joint was secondary to juxtaarticular plexiform
neurofibroma with massive invasion of the right sacroiliac joint.
Bajo anestesia general se realizo la diseccion hasta la aponeurosis cervical profunda con diseccion del paquete vasculonervioso cervical (arteria carotida, vena yugular interna y nervio neumogastrico), logrando la reseccion del
neurofibroma, tumor solido de consistencia dura, forma ovalada y sin abundante vascularizacion (figura 3).
Abstract: Peripheral nerve sheath tumors are a heterogeneous group of neoplasms that comprise
neurofibromas, schwannomas, neurilemmomas, and perineuromas.
Lesions like bronchogenic cyst and
neurofibroma were suspected by CT imaging, but surgical excision proved to be both diagnostic and therapeutic.
Neurofibroma lacks capsule, rich in mucopolysaccharide ground substance and has fewer axons.
An incision biopsy from the posterior mandibular lesion which microscopically revealed interlacing bundles of spindle shaped cells with wavy nuclei, delicate collagen fibres, plump fibroblasts, and a strong positive reaction with S-100 (detection system, HRP polymer) confirmed the diagnosis of simple
neurofibroma (Figures 2(a) and 2(b)).
18-FDG-PET-CT scan helps in differentiating MPNST from benign
neurofibroma in NF-1 patients and detecting malignant transformation of benign plexiform
neurofibromas [1, 3].
The schwanoma and
neurofibroma differ histologically and histogenetically; the schwannoma is derived from the Schwann cells and the
neurofibroma from the fibroblasts of the perineurium.
Pigmented
neurofibroma can be differentiated from Bednar tumour by more extensive storiform growth and strong positivity for CD34 in latter.
