Neurohormone


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neurohormone

[¦nu̇r·ō′hȯr‚mōn]
(neuroscience)
A hormone produced by nervous tissue.

Neurohormone

 

a physiologically active substance that is produced by special neurons—the neurosecretory cells.

Like a mediator substance (chemical transmitter), a neurohormone is released by nerve endings, but in contrast to the first, a neurohormone is secreted into the blood or tissue fluid. Such secretion into the body fluids is characteristic of hormones. Neurohormones, for example, vasopressin, oxytocin, and the adenohypophysiotropic hormones, have been discovered in many vertebrates and in many invertebrates, including mollusks, worms, and arthropods. Chemically, the majority of neurohormones are peptides; some are catecholamines. Biosynthesis of peptide neurohormones occurs in the endoplasmic reticulum of the cell body of the neuron, The peptides are packaged in the Golgi complex and are subsequently transported along the axon to the nerve endings. In the mammalian brain the neurosecretory cells of the hypothalamus are a source of neurohormones. Neurohormones regulate the activity of the cells of some endocrine glands and influence the cells of other organs.

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This neurohormone messenger endorphin influence is more of a balancing act.
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vascular smooth muscle, liver, and kidney) from nerve terminals in the posterior pituitary (Goldsmith 1987; Haslam and Rosson 1972) Peripherally circulating AVP is responsible for the classic endocrine functions ascribed to this neurohormone (e.
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Data on the influence of antineurohormonal therapy on neurohormone concentrations are widely divergent.
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Researchers are investigating if this neurohormone secretion is the cause of neuropsychiatric disorders developing in some patients with borreliosis.
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For these reasons, BNP might show a better correlation with rapid changes in activation of neurohormone systems and hemodynamics than NT-proBNP.