enolase

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enolase

[′ē·nə‚lās]
(biochemistry)
An enzyme that catalyzes the reversible dehydration of phosphoglyceric acid to phosphopyruvic acid.
References in periodicals archive ?
S-100 protein and neuron-specific enolase in cerebrospinal fluid and serum: markers of cell damage in human central nervous system.
Immunohistochemical results for antigen tests using vimentin, neuron-specific enolase (NSE), SI00, and glial fibrillary acidic protein (GFAP) in a 5-year-old, female golden eagle with tetraplegia.
Neuron-specific enolase, a dimeric cytoplasmic isoenzyme has been shown to be located in neurons and neuroectodermal tissue.
10-12) Typical immunohistochemical findings include positivity for vimentin, CD99, FLI1, and variable reactivity for neuron-specific enolase, CD57, synaptophysin, and cytokeratin.
Biomarkers such as neuron-specific enolase (NSE) and myelin basic protein (MBP), which are candidate markers for shaken baby syndrome and other types of neurotrauma, will be studied.
Neuron-specific enolase in gerbil brain and serum after transient cerebral ischemia.
3) Although the histogenesis of GCT is unknown, immunohistochemical stains (positive for S-100 protein, neuron-specific enolase, NK1-C3, and so forth) and ultrastructural findings (eg, myelin residues, long-spacing collagen, arrays of neuritic processes among tumor cells) indicate neural (Schwann cell) derivation of GCT.
Neuron-specific enolase has been shown to stain positive in 95% of renal PNET cases.
The tumor cells were strong diffusely immunostained with both neuron-specific enolase and neurofilament protein and partially for synaptophysin.
Other helpful markers are neuron-specific enolase and vimentin, synaptophysin and S100 protein.
Ischemic injury to the central nervous system causes cellular activation and disintegration, leading to release of cell-type-specific proteins such as myelin basic protein (MBP), [8] glial fibrillary astrocytic protein (GFAP), the calcium-binding protein S100B, and neuron-specific enolase (NSE).
CD99 and vimentin are almost always expressed in ES/PNET, while neuron-specific enolase and synaptophysin are expressed less often.

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