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Related to Neuropathy: Alcoholic neuropathy, diabetic neuropathy


Any disease affecting neurons.



a functional weakness of the nervous system accompanied by a decrease in the absolute threshold (also called the stimulus, or sensitivity, threshold); the condition is frequently congenital.

Neuropathy arises as a disturbance in the function of the autonomic nervous system owing to deleterious influences on the fetus as a whole (for example, infection in the pregnant mother, trauma, or poisoning) or on the individual embryonic cells (as occurs when the parents suffer from alcoholism). Family circumstances, upbringing, and illnesses suffered by the infant play a role in the pathogenesis of neuropathy. The symptoms usually emerge in childhood or adolescence. When neuropathy occurs in early childhood, disturbances of sleep and appetite are most characteristic; the infant has difficulty in falling asleep, awakes easily, suckles poorly, and frequently spits up. Later, vomiting occurs, and either diarrhea or constipation develop.

From the preschool years on, increased general excitability and the rapid onset of fatigue and exhaustion are observed, in addition to continued disturbances of sleep and appetite. Children who suffer from neuropathy blush easily in response to irritation. Motor hyperactivity, nervous tics, and stammering are frequent. In adolescence, autonomic-vascular instability becomes more acute, as evidenced by frequently occurring nervous palpitation, abrupt shifts in blood pressure, headaches, dizzy spells, and fainting spells. The prognosis is favorable, with the neuropathic symptoms usually disappearing with age.


Simson, T. Nevropatii, psikhopatii i reaktivnye sostoianiia mladencheskogo vozrasta. Moscow-Leningrad, 1929.
Sukhareva, G. E. Klinicheskie lektsii po psikhiatrii detskogo vozrasta, vol. 2. Moscow, 1959.


References in periodicals archive ?
The most common peripheral neuropathy in advanced nations is diabetic neuropathy.
Characterization of virus isolated from the cerebrospinal fluid of patients with epidemic neuropathy.
Coverage of the Leber's Hereditary Optic Neuropathy (LHON) (Leber optic atrophy) pipeline on the basis of route of administration and molecule type.
And because so many neuropathy patients have been shuffled from doctor to doctor with no hope for a solution, we wanted the Neurogenx treatment experience to be entirely different," added London.
Those who could feel neither monofilament had severe neuropathy.
The cause of diabetic neuropathy is still controversial, in that evidence has see-sawed over the years, strongly favoring at one time that the nerve damage was due to blockage of small blood vessels--the result of diabetes and, more recently, that the cause of diabetic neuropathy is inflammation in the nerves.
12] level--the odds ratio for having peripheral neuropathy was 1.
The immune system, glucose concentrations, and other factors may all contribute to diabetic neuropathy, he notes.
A snapshot of the global therapeutic scenario for Diabetic Peripheral Neuropathy.
CHICAGO -- Lipid-lowering therapy was associated with a significant reduction in the risk of developing peripheral sensory neuropathy in a large Australian observational study of adults with type 2 diabetes mellitus.
com/research/7n6xpp/chemotherapy) has announced the addition of Global Markets Direct's new report "Chemotherapy Induced Peripheral Neuropathy - Pipeline Review, H2 2012" to their offering.
In people with autonomic neuropathy, symptoms may not occur, making hypoglycemia difficult to recognize.