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Nervous tissue consisting of a fibrous network of nonmyelinated nerve fibers; gray matter with few nerve cell bodies; usually a region of synapses between axons and dendrites.



(1) An obsolete term designating a fibrous nerve tissue structure that is found predominantly in invertebrates. The supposedly interconnected nerve fibers form a continuous cytoplasmic network that resembles a syncytium. This use of the term “neuropil” does not accurately reflect the microstructure of the nervous system. (See.)

(2) The fibrous nerve tissue structure in which synaptic contacts between neuronal outgrowths are concentrated.

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Both 5-HT and FMRF-amide immunoreactive nerve fibers were also observed throughout the neuropils of the ganglia.
16) As one might expect, the neuropil islands are distinguished by strong immunostaining for synaptophysin, and nuclei of cells embedded in the islands may show reactivity for neuN and anti-Hu (Figures 10 and 11).
Second, they suggest that the brain possesses clearance mechanisms that can compensate for the abnormal generation of A[Beta] for many years before this peptide becomes deposited in the neuropil.
When tau is hyperphosphorylated, primarily by the action of serine/threonine kinases, it dissociates from microtubules, leading to the formation of paired helical fragments that, in turn, aggregate into neurofibrillary tangles and neuropil threads (4).
Extracellular and Connective Tissue Components Background stroma Neuropil Neuroblastoma Desmoplasia Desmoplastic small cell tumor Myxoid Liposarcoma, embryonal rhabdomyosarcoma Calcifications Neuroblastoma, synovial sarcoma, and MNST Lymphoglandular Non-Hodgkin lymphoma bodies Other elements Neuronal cells Neuroblastoma, ectomesenchymoma Rhabdomyoblasts Rhabdomyosarcoma Cross-striations Rhabdomyosarcoma Blastema/ Nephroblastoma, pleuropulmonary epithelium blastoma Abbreviation: MNST, malignant nerve sheath tumor.
The generalized histopathology reveals spongiform degeneration in the neuropil of the brain and spinal cord.
This space (the neuropil) represents 90-98% of the volume of the human cerebral cortex, with an estimated 1bn synapses per cubic nanometer of neuropil.
Neuropil distribution in the cerebral cortex differs between humans and chimpanzees.
Varicose GABA-ir fibers could be seen in the neuropil areas and in distinct areas of the cell body layer of the ganglia.
We will start by analysing the function, development and connectivity of a newly characterized class of inhibitory interneurons located in the superficial part of the tectal neuropil named SINs (superficial inhibitory interneurons) that I have previously identified.
Primitive neuroectodermal tumours are members of the Ewing's sarcoma family composed of small round cells normally lacking morphologic evidence of neuroblastic differentiation in the form of neuropil or ganglion cell formation.
The reduction in hippocampal volume is attributable to decreased neurogenesis, death or atrophy of existing neurons, changes in neuropil, the number of synapses, and synaptic bulk (Sapolsky 2000; Kempermann 2001).