neurotoxin

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neurotoxin

[¦nu̇r·ō′täk·sən]
(biochemistry)
A poisonous substance in snake venom that acts as a nervous system depressant by blocking neuromuscular transmission by binding acetylcholine receptors on motor end plates, or on the innervated face of an electroplax.
References in periodicals archive ?
This work is part of Ipsen's commitment to apply modern protein engineering and recombinant protein expression to enable development of novel and improved botulinum neurotoxin products for increased therapeutic utility and patient care".
Understanding the driving forces for the future of the botulinum neurotoxin market;
Mercury is a potent neurotoxin that exerts a synergistic amplifying effect on all other neurotoxins.
The five strains were remarkably similar in the area of the genome containing the neurotoxin gene.
If botulinum neurotoxin is produced in the infant gut it is transported to the neuromuscular junction, leading to flaccid muscle paralysis that in infants is known as floppy baby syndrome.
Botulinum neurotoxins are the most poisonous poison known to the humankind produced by strains of C.
Turley added: "Unlike neurotoxin agents, which have to be injected periodically, a localized injection of a RHAMM inhibitor should produce long-lasting skin volumizing effects and would not involve muscle paralysis, which means there would be no loss of expression if it were to be injected into the face.
Consistent with this view, endogenous neurotoxins (R)-Sal and (R)-NMSal have been considered to be responsible for the massive depletion of dopaminergic neurons and participate in the pathogenesis of PD.
Neurotoxins frequently cause inflammation, damage hormone pathways, and affect the immune system.
High affinity binding of red tide neurotoxins to marine mammal brain.
This chemical disruption is a trait common to many neurotoxins.
It makes a "probable link" to neurotoxins and says one source is likely to be the nerve gas sarin - to which troops were exposed after an airstrike on an Iraqi chemical weapons factory.