Newcastle disease


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Newcastle disease,

pneumoencephalitis, acute viral disease of domestic poultry. Newcastle disease is characterized by sneezing, coughing, and nervous behavior. Affected birds may show tremors, circling, falling, twisting of the head and neck, or complete paralysis. Mortality reaches 90% in very young birds but adult mortality is very low. Among affected laying hens, egg quantity and quality drop sharply at first but usually return to former levels within four to eight weeks. In humans the virus causes only a temporary conjunctivitis. The disease can be controlled in poultry by sanitary management and isolation of flocks, and by live-virus and inactivated vaccines administered by injection or in eye-drops, aerosol sprays, or drinking water.
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Newcastle disease

[′nü‚kas·əl di‚zēz]
(veterinary medicine)
An acute viral disease of fowls, with respiratory, gastrointestinal, and central nervous system involvement; may be transmitted to human beings as a mild conjunctivitis. Also known as avian pneumoencephalitis; avian pseudoplague; Philippine fowl disease.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Global Newcastle Disease Vaccine market competition by top manufacturers, with production, price, revenue (value) and market share for each manufacturer; the top players including
Samal, "Newcastle disease virus fusion protein is the major contributor to protective immunity of genotype-matched vaccine," PLoS One, vol.
Newcastle disease virus is a single stranded RNA with negative sense withat least three genomic lengths, 15186 (Paldurai et al., 2010), 15189 (Yurchenko et al., 2015)15192 (Wajid et al., 2015, Umali et al., 2014) and 15198 (Kim et al., 2012) and encodes for nucleocapsid protein (NP), phosphor-protein (P), matrix protein (M), fusion protein (F), haemagglutini-neuroaminidase protein (HN), and large protein (L) (Shabbiret al., 2013; Miller et al., 2010).
[1.] Alexander, D.J., Newcastle disease. In: Rweyemamu, M.M., Palya, V, Tin Win (Eds.), Proceedings of a Workshop on Newcastle Disease Vaccines for Rural Africa, 1991.
A total of five birds from each experimental group were selected randomly and exposed to field isolate of Newcastle Disease Virus at dose rate of 1000 EID50 per ml at day 45.
Using the same method for developing the H5N1 vaccine, researchers inserted a small section of the H7N9 virus into the Newcastle disease virus vaccine.
** Research Project: Evaluation of Recombinant Newcastle Disease Vaccines (Ndv)
"If you see birds staggering around and looking nervous, if they have swollen, puffy eyes and heads start to swell, or if you have a large flock and the number of eggs produced is significantly lower than it should be, call the vet who can tell you if it is likely to be avian flu or Newcastle disease and then you can call the Animal and Plant Health Agency.
Out of 210 broiler flocks 22, 5, 2 broiler flocks were affected with Newcastle disease, Gumboro and Hydropericardiumsyndrome respectively.
Newcastle disease (ND) is a highly contagious viral infection of avian species especially poultry caused by Newcastle disease virus (NDV), a Paramyxovirus called avian Paramyxovirus type 1 (APMV-1).
Newcastle disease virus (NDV) is an economically devastating pathogen in the global poultry industry [1, 2].

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