It increases the risk of heart disease and if left untreated, it can lead to nonalcoholic steatohepatitis
(NASH), a condition causing inflamed liver.
Zhang et al., "The ameliorating effect of rosiglitazone on experimental nonalcoholic steatohepatitis
is associated with regulating adiponectin receptor expression in rats," European Journal of Pharmacology, vol.
Gill et al., "Characterization of gut microbiomes in nonalcoholic steatohepatitis
(NASH) patients: a connection between endogenous alcohol and NASH," Hepatology, vol.
[17.] Bacon BR, Farahvash MJ, Janney CG, Neuschwander-Tetri B Nonalcoholic steatohepatitis
: An expanded clinical entity.
Anania et al., "World gastroenterology organisation global guidelines: nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
," Journal of Clinical Gastroenterology, vol.
Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis
. N Engl J Med.
Among 62 people with HIV and persistently high liver enzymes--but without hepatitis virus infection--73% had nonalcoholic fatty liver disease (NAFLD), 55% had nonalcoholic steatohepatitis
(NASH), and 18% had advanced fibrosis.
In the other study, researchers in France found that nonalcoholic steatohepatitis
disappeared in 85 percent of obese patients one year after they had weight-loss surgery.
* The Nonalcoholic Steatohepatitis
(NASH) EpiCast Report provides an overview of the risk factors and global trends of NASH in the 6MM (US, France, Germany, Italy, Spain, and UK).
Early detection of nonalcoholic steatohepatitis
in patients with nonalcoholic fatty liver disease by using MR elastography.
The Virginia Commonwealth University School of Medicine (VCU) findings may provide researchers with potential new targets for treatment and also allow clinicians to further refine how they assess cardiovascular risk and develop ways to reduce it in individuals with a more aggressive form of nonalcoholic fatty liver disease called nonalcoholic steatohepatitis
, or NASH.
The combination might also increase a patient's risk of nonalcoholic steatohepatitis