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Related to Nontuberculous mycobacteria: Mycobacterium marinum



a genus of bacteria, related to actinomycetes; it differs from true bacteria in a number of ways. The young vegetative cells are rodlike (0.5–0.8 × 2.2 microns); they are capable of branching and acquiring V or Y shapes. In old cultures spherical cells predominate. Mycobacteria, which do not form endospores, are nonmotile, gram-positive, and strictly aerobic. They reproduce mainly by dividing and budding. Mycobacteria contain carotenoids, and, as a result, their colonies are often pigmented (yellow, orange, or red). Owing to their cell composition (including lipides and wax), some myco-bacteria, in contrast to other bacteria, are acid-fast.

Mycobacteria are widely distributed in soils and are active in the mineralization of plant remains. Some species of Mycobacterium are nitrogen-fixing microorganisms; others are capable of metabolizing the carbohydrates of petroleum and natural gas and, when cultured, accumulate protein, which is used for fodder and other purposes. Some species of Mycobacterium are pathogenic to humans (for example, mycobacteria are the causative agents of tuberculosis and leprosy).


References in periodicals archive ?
Average number of patients per year who had nontuberculous mycobacteria isolated, by body site and species-complex, Ontario, Canada, 1998-2010 * Species Pulm Skin/soft tissue MS Lymph MAC 1,328 8 1 2 Mycobacterium xenopi 568 0.
Nontuberculous mycobacteria from household plumbing of patients with nontuberculous mycobacteria disease.
In all the cultures with identified nontuberculous mycobacteria, Mycobacterium xenopi, Mycobacterium fortuitum, Mycobacterium avium, the test results were negative.
In contrast to tuberculosis, which is spread by coughing, the nontuberculous mycobacteria appear to be acquired from the environment.
The count of nontuberculous mycobacteria in water samples have been determined to be 1 to 20 colonies in 500 ml (13).
If inhibitors are not detected and additional specimens remain NAA-negative, the patient can be presumed to have nontuberculous mycobacteria.
When TB PNA FISH was evaluated with 30 acid-fast bacillus-positive (AFB(+) cultures from Denmark and 42 AFB(+) cultures from Thailand, 87% of the cultures were correctly identified as Mycobacterium tuberculosis complex (n = 46) or nontuberculous mycobacteria (n = 17).
Nontuberculous mycobacteria (NTM) are prominent human pathogens, with >150 species reported worldwide (1).
The US Food and Drug Administration has granted Qualified Infectious Disease Product (QIDP) fast-track designation to Israel-based RedHill Biopharma's (NASDAQ / TASE: RDHL) RHB-104, intended to treat nontuberculous mycobacteria infections, it was reported on Friday.
The pipeline also includes MP-376, known commercially as QUINSAIR, which has Qualified Infectious Disease Product (QIDP) designation for three distinct indications: the treatment of chronic pulmonary infections due to Pseudomonas aeruginosa, in patients with CF and in patients with BE, and in patients with nontuberculous mycobacteria (NTM).