Normoblast

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Related to Normoblasts: polychromatophilic erythroblast

normoblast

[′nȯr·mə‚blast]
(histology)
The smallest of the nucleated precursors of the erythrocyte; slightly larger than a mature adult erythrocyte. Also known as acidophilic erythroblast; arthochromatic erythroblast; eosinophilic erythroblast; karyocyte; metakaryocyte; metanitricyte; metarubricyte.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Normoblast

 

one of the stages in the maturation of erythrocytes in the bone marrow of mammals and man. The cytoplasm of a developing normoblast gradually becomes enriched with hemoglobin and the nucleus degenerates, resulting in the emergence of a mature erythrocyte.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Pluripotential stem cell Myeloid Progenitors Myeloblast Monoblasts Marrow pool Mitotic Promelocytes Promonocytes precursors Myelocytes Post-mitotic Metamyelocytes bands Blood and Neutrophils, Monocytes tissue eosinophils and function basophils Innate Macrophage immunologic function Progenitors Megakaryocyte Erythroid Lymphoid Marrow pool Mitotic Maturing Normoblasts Pre-B precursors megakaryocytes Post-mitotic Reticulocytes B lymphoblast Blood and Platelets Erythrocytes B tissue lymphocytes function and plasma cells Haemostasis Oxygen Adaptive transport immunologic function Progenitors Marrow pool Mitotic Pro-T precursors Post-mitotic Lymphoblast Blood and T-lymphocytes tissue and NK cells function Fig.
A complete blood cell count showed a leukocyte count of 6,110/[micro]L (4% bands, 77% segmented neutrophils, 7% lymphocytes, 6% normoblasts, and 3% myelocytes), hemoglobin level of 11.5 g/dL, and platelet count of 3,000/[micro]L.
Compared with simple [beta]-heterozygotes, co-inheritance of triplicated or quadruplicated [alpha]-globin genes in [beta]-heterozygotes often leads to more significant anemia, splenomegaly, more pronounced red cell abnormalities, the presence of circulating normoblasts, higher hemoglobin F concentrations, and even the presence of inclusion bodies in erythroblasts (3,4).
Erythropoietic (Congenital) Porphyria: A Rare Abnormality of the Normoblasts. Blood, 10(3):416-428.
In addition to the sickled RBCs, 13 had normoblasts and polychromasia, 15 had neutrophilic leucocytosis and 12 had thrombocytopenia.
(22) Chorangiosis has statistically nonsignificantly clustered with preuterine hypoxia, multiple pregnancy, and normoblasts in fetal circulation.
The slides were entirely scanned with 100x oil-immersion lens for abnormal nucleated cells such as blast cells, normoblasts, or immature granulocytes and, if any were found, the samples were excluded from the study.
Few normoblasts were seen in HbSS, but seen occasionally in HbSA.
There are fewer numbers of circulating reticulocytes and normoblasts in fetuses and newborns with anti-K disease than in fetuses with anti-D HDFN (7).
Normoblasts may or may not be observed in the blood smear.