Pluripotential stem cell Myeloid Progenitors Myeloblast Monoblasts Marrow pool Mitotic Promelocytes Promonocytes precursors Myelocytes Post-mitotic Metamyelocytes bands Blood and Neutrophils, Monocytes tissue eosinophils and function basophils Innate Macrophage immunologic function Progenitors Megakaryocyte Erythroid Lymphoid Marrow pool Mitotic Maturing Normoblasts
Pre-B precursors megakaryocytes Post-mitotic Reticulocytes B lymphoblast Blood and Platelets Erythrocytes B tissue lymphocytes function and plasma cells Haemostasis Oxygen Adaptive transport immunologic function Progenitors Marrow pool Mitotic Pro-T precursors Post-mitotic Lymphoblast Blood and T-lymphocytes tissue and NK cells function Fig.
Compared with simple [beta]-heterozygotes, co-inheritance of triplicated or quadruplicated [alpha]-globin genes in [beta]-heterozygotes often leads to more significant anemia, splenomegaly, more pronounced red cell abnormalities, the presence of circulating normoblasts
, higher hemoglobin F concentrations, and even the presence of inclusion bodies in erythroblasts (3,4).
Erythropoietic (Congenital) Porphyria: A Rare Abnormality of the Normoblasts
Reagent solutions and related supplies for the analyzer must allow the implementation of blood analysis, 5-population differential budget, immature forms of leukocytes, reticulocytes and normoblasts
in peripheral blood for hematology laboratory EUKBH LochotE[degrees]n Hospital Pilsen.
The slides were entirely scanned with 100x oil-immersion lens for abnormal nucleated cells such as blast cells, normoblasts
, or immature granulocytes and, if any were found, the samples were excluded from the study.
Clusters of normoblasts
(extramedullary hematopoiesis) are commonly seen, as in fetal liver.
The prominent finding was erythroid hyperplasia, demonstrated by an increased number of red cell precursors: pronormoblasts and few polychromatophilic normoblasts
and orthochromic erythroblasts.
Effect of deoxyuridine on incorporation of tritiated thymidine: difference between normoblasts