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While the platelet count also seemed to be recovering, there was a normocytic normochromic anaemia with haemoglobin falling to 94 g/L.
The anemia of copper deficiency often is associated with the presence of ringed sideroblasts and occurs in a number of clinical settings, including a microcytic, macrocytic, or normocytic anemia.
Laboratory tests were normal besides a normochromic, normocytic anemia with 35% hematocrit and 48 mm/h erythrocyte sedimentation rate.
Clinically, patients with Addison's disease-which results in a lack of glucocorticoid production-have been shown to have normocytic anaemia, whereas patients with Cushing's disease-involving redundant glucocorticoid production-show increased numbers of erythrocytes and elevated hematocrit concentration (1-4).
6,8,9) Anemia is another hematological manifestation noted, and the most common type being a mild normocytic anemia of chronic inflammation.
A variety of reversible hematologic abnormalities--such as anemia (macrocytic, normocytic, and microcytic), leukopenia, neutropenia, and thrombocytopenia, as well as pancytopenia--may result from copper deficiency.
RBC morphology is normocytic and normochromic unless complicated by iron deficiency.
In a case series of 225 patients undergoing primary THR, 35 were anaemic: 60% were iron deficient, 34% had a normochromic normocytic anaemia and 6% had a macrocytic anaemia.
He was found to have a normocytic anaemia, which had improved after being prescribed ferrous sulphate.
The role of erythropoietin in patients with normocytic, normochromic anaemia in HF is being evaluated.