Notch signaling


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Notch signaling

[′näch ‚sig·nəl·iŋ]
(embryology)
An evolutionarily conserved developmental pathway utilized during the differentiation of a plethora of tissue types, in organisms as diverse as nematodes and humans.
References in periodicals archive ?
23,24) We have previously shown that Notch ligands such as delta like 1 (Dll1) and jagged1 (Jag1) are expressed in NSC-produced neuroblasts or immature neurons, and they activate Notch signaling in adjacent remaining NSCs.
His research focused on neural development and notch signaling in mammalian neural stem cells.
The sonic hedgehog, homeobox gene Pdx1, and Notch signaling systems are effective in the development of the pancreas (43, 44).
This application takes its initiation in two recent discoveries that we have made: that astrocytes in the mouse striatum give rise to new neurons after stroke or inhibition of Notch signaling (Magnusson et al.
Notch-regulated ankyrin repeat protein (NRARP) is a negative feedback regulator in Notch signaling pathway and regulated by Notch protein.
Caption: Figure 2: Western blot was performed for Notch signaling and cardiomyocyte- specific markers in MSCs, [MSC.
demonstrated the pivotal role of Notch signaling pathway in mitigating burn-induced myocardial tissue in a rodent model.
MSC Transplantation Improves Osteopenia via Epigenetic Regulation of Notch Signaling in Lupus;" Cell Metabolism, Vol.
Smiti discovered that delta-tocotrienol extracted from palm oil showed potential in inhibiting non-small cell lung cancer cell growth via Notch signaling, which refers to a highly-conserved cell signalling system present in most multicellular organisms.
Recent evidence suggests that Notch signaling is important in a mouse model of allergic asthma.
A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse.