SIRT1 cascade improves post-ischaemic vascular repair by modulating Notch signalling
in endothelial progenitors," Cardiovascular Research, vol.
during peripheral T-cell activation and differentiation.
BMPs and FGFs target Notch signalling
via Jagged2 to regulate tooth morphogenesis and cytodifferentiation.
The Notch signalling
pathway plays an important role in the processes of cell fate determination, including stem cell maintenance, differentiation, proliferation and apoptosis, which may contribute to the carcinogenesis of osteosarcoma.
The Notch signalling
pathway is referred to as the 'aristocracy' on the 'social ladder' of pathways due to its preservation amongst the species and importance in both embryonal development and adult function .
Conservation of the Notch signalling
pathway in mammalian neurogenesis," Development, vol.
They investigated the effect of a known signalling pathway called NOTCH on muscle differentiation, and found that differentiation of stem cells to muscle was initiated when NOTCH signalling
proteins touched some of the cells.
controls pancreatic cell differentiation.
The authors have studied Notch signalling
(part of the developmental signalling pathway) and showed a relationship to an inhibitor of the apoptosis gene family, namely survivin.
There are very few molecules that we know directly inhibit Notch signalling
from one of the groups that has pioneered breast cancer stem cell research, describe the dysregulated pathways, such as the Notch signalling
pathway, and the connection between Notch pathway activation of breast cancer stem cells, stem cell self-renewal pathways and how this might lead to novel therapeutic targets in both pre-invasive and invasive breast cancer.
London, June 22 (ANI): Researchers at Baylor College of Medicine say that they have made a new finding regarding the Notch signalling
pathway in sensory organ precursor cells in the fruit fly that may help unravel the mystery behind an immunological disorder called WisKott-Aldrich syndrome.