nuclear hormone receptor

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nuclear hormone receptor

[¦nü·klē·ər ′hȯr‚mōn ri‚sep·tər]
(cell and molecular biology)
Any of a superfamily of proteins that directly regulate transcription in response to hormones and other ligands.
References in periodicals archive ?
The findings indicated that the drug zeroes in on mutated nuclear receptors found in cancer, leaves normal proteins alone.
According to the company, the NR2F6 nuclear receptor has been identified as a potentially important immune cell inhibitor (an immune checkpoint) and cancer stem cell differentiator.
Published in the August issue of The Journal of Clinical Investigation (JCI), the study showed that when the researchers blocked the effects of the nuclear receptor PPARgamma in a small number of brain cells in mice, the animals ate less and became resistant to a high-fat diet.
Cell-based INDIGO Nuclear Receptor Assay Kits are available for purchase in North America directly and worldwide through partnerships with leading distributors.
The story for nuclear receptors is similar, with the most commonly cited proteins remaining the same over the last 10 years.
of Aberdeen, UK), 14 contributions are presented in sections dedicated to ligand binding and nuclear receptor turnover, nuclear localization and DNA binding, nuclear receptor--co- regulatory protein interactions, and pathophysiological analysis of nuclear receptor function.
This protein can bind to several other nuclear receptors to form distinct molecular complexes called heterodimers.
The LXR beta nuclear receptor was developed jointly by Karo Bio and the US healthcare group American Home Products Corp under a collaboration agreement signed last September.
the industry's leading provider of cell-based nuclear receptor reporter assay products and services, has added all nine retinoid receptor assays to the company's significant suite of kits and screening services.
18 September 2014 - US nuclear receptor screening specialist Indigo Biosciences said Thursday it had launched a human estrogen-related orphan receptor gamma (NR3B3; ERR?
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