nucleophilic substitution

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nucleophilic substitution

[‚nü·klē·ə¦fil·ik ‚səb·stə′tü·shən]
(organic chemistry)
A reaction in which a nucleophile bonds to a carbon atom in a molecule, displacing a leaving group. Also known as nucleophilic displacement.
References in periodicals archive ?
4a) is characterized by nucleophilic substitution reaction with the formation of a CPL molecule as by-product, while the second mechanism (Fig.
The first mechanistic proposal for the process of phase-transfer catalysis was formulated by Starks [1, 3] for a liquid-liquid system (LL-PTC) using a nucleophilic substitution reaction (Scheme 1).
With the chlorotriazine reactive group, the Cl group is replaced by the Cell-O- group through a nucleophilic substitution reaction.
This enabled to achieve intensification of the nucleophilic substitution reaction with high volume productivity and critical control of process condition which in batch manner takes more than 3 hr.
The branched polystyrene is produced by a nucleophilic substitution reaction of active methylene groups with bonded electron-attracting groups.
Since quaternary ammonium salts are obtained by simple nucleophilic substitution reaction of an alkyl/aryl halide with a tertiary amine, variety of quaternary ammonium salts can be obtained by changing either of the two components.
A novel series of imine-diols (D-1, D-2, D-3, D-4, D-5,D-Ar) having inbuilt aliphatic and aromatic segments were prepared via two-step process involving nucleophilic substitution reaction between dibromoalkanes and 4-hydroxybenzaldehyde leading to the formation of dialdehydes and then its acid catalyzed reaction with 4-hydroxyaniline.
2] type nucleophilic substitution reaction with contemporary formation and breakage of molecular bonds.
1,3Benzodioxol5amine (1) was subjected to nucleophilic substitution reaction with tosyl chloride (2) in water.
Among their topics are addressing the challenges of stand-alone multi-core simulations in molecular dynamics, an analytical solution of the pantograph equation with incommensurate delay, the mechanism of nucleophilic substitution reactions of 4-(4'-nitro) phenylnitrobenzofurazan ether with aniline in acetonitrile, computational methods in pre-formulation study for pharmaceutical solid dosage forms of therapeutic proteins, and elemental two-dimensional materials beyond graphene.
Summary: This study comprises the synthesis and characterization of twenty thiazole-derived carbamates (3a-e), N-substituted amides (8a-h) and carboxamide (10) from 2-aminothiazoles (1a, b) via nucleophilic substitution reactions with activated carbonyl compounds including, chloroformates (2a-d), acid chlorides (7a-e) and glutaric anhydride (9), respectively.