melanoma

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melanoma:

see skin cancerskin cancer,
malignant tumor of the skin. The most common types of skin cancer are basal cell carcinoma, squamous cell carcinoma, and melanoma. Rarer forms include mycosis fungoides (a type of lymphoma) and Kaposi's sarcoma.
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Melanoma

 

melanoblastoma; a malignant tumor that consists of melanin-producing cells.

Factors conducive to the development of melanomas include injury and hormonal stimulation, especially during puberty. Melanomas generally occur on the skin; less often, they appear on the retina, pia mater, nasopharynx, larynx, esophagus, and mucosa of the intestine and other organs. Melanomas usually develop at the site of pigmented or depigmented birthmarks, but they may also appear elsewhere. The process starts with a barely perceptible, painless tumor on the skin, sometimes resembling a wart, which gradually becomes dark brown or black. Occasionally, it ulcerates and bleeds. In case of injury, the tumor may enlarge quickly and become tuberous, dense at the base, and stiffer. The regional lymph nodes enlarge. The initial signs that a melanoma is developing at the site of a birthmark are the birthmark’s enlargement, an intensification or reduction in its pigmentation, and the appearance of a red rim around it. Treatment involves prompt surgical intervention, based on early diagnosis, and the use of radiotherapy and drugs to retard the growth and reproduction of the cells.

I. IA. SHAKHTMEISTER

melanoma

[mel·ə′nō·mə]
(medicine)
A malignant tumor composed of anaplastic melanocytes.
A benign or malignant tumor composed of melanocytes.

melanoma

Pathol a malignant tumour composed of melanocytes, occurring esp in the skin, often as a result of excessive exposure to sunlight
References in periodicals archive ?
campaign was spearheaded by the MRF's CURE Ocular Melanoma (CURE OM) initiative, which was founded in 2011 to increase OM awareness, research funding and patient and caregiver education and support.
Isolated hepatic perfusion with high-dose melphalan results in immediate alterations in tumor gene expression in patients with metastatic ocular melanoma.
In a second series of experiments, the researchers found that if they put ocular melanoma cells in culture and depleted their supply of BAP1, the cells began to change in appearance and to resemble class 2 tumors in just five days.
to investigate the Melphalan/HDS system for the treatment of primary liver cancer (HCC) and intrahepatic cholangiocarcinoma (ICC), and expect to initiate a global Phase 3 trial in ocular melanoma (OM) that has metastasized to the liver.
This encouraging clinical activity suggests that ocular melanoma is an important subgroup of melanoma for IMCgp100 based on the high unmet need in this indication.
TUESDAY was Eye Patch Day to raise awareness of a rare form of cancer called Ocular Melanoma.
34, passed away April 4, 2014 following a lengthy battle with Ocular Melanoma.
Recently, an early oncogenic mutation has been identified in ocular melanomas.
Studies provide consistent evidence of a positive association between the use of UV-emitting tanning devices and ocular melanoma - skin cancer of the eyelid.
Three conditions usually exist that help identify a tumor as a primary malignant melanoma: (1) the tumor should be the dominant lesion, (2) there may be local and regional metastasis, and (3) the patient should have no history of a primary cutaneous or ocular melanoma or nevus that regressed spontaneously.
It led to him being told he had a rare and aggressive form of eye cancer, called ocular melanoma, and that he only had two years to live.
5) Understands the implications of the manifestations of eye disease including diabetes and ocular melanoma