Oleandomycin


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oleandomycin

[‚ō·lē‚an·də′mīs·ən]
(microbiology)
C35H61O12N A macrolide antibotic produced by Streptomyces antibioticus ; active mainly against gram-positive microorganisms. Also known as matromycin.

Oleandomycin

 

a macrolide antibiotic that is isolated from the culture fluid of the actinomycete Streptomyces antibioticus. Oleandomycin suppresses the growth of gram-positive bacteria, primarily staphylococci, streptococci, and pneumococci. When oleandomycin is combined with tetracycline, the antimicrobial action is potentiated. Oleandomycin is used in infectious diseases of the lungs and of the urinary and biliary tracts; it is also used in other diseases that are caused by microbes that are resistant to antibiotics and sensitive to oleandomycin. Oleandomycin is effective against the same spectrum of bacteria as erythromycin.

References in periodicals archive ?
Where as sensitivity was observed with oleandomycin, neomycin and penicillin-G.
In this study, erythromycin, tylosin, and oleandomycin were selected to study both types of fragmentations.
37-40[degrees]C, optimum pH 7, range of NaCl concentration 0.5-3.5M, needed Mg[Cl.sub.2], optimum Mg[Cl.sub.2], 20%, utilize glucose, fructose, sucrose, citrate, Mannitol, maltose and lactose, hydrolyze DNA, Oxidase and Catalase were produced; resistance for antibiotics Oleandomycin and Oxacillin, H5 produced HZS.
* human-medicine antibiotics currently used in livestock and poultry food include arsanilic acid, avoparcin, bacitracin, bam bermycin, chlortetracycline, erythromycin, furazolidone, glycopeptides, lincomycin, neomycin sulfate, nitrofurazone, 3-nitro-4-hydroxy phenylarsonic acid, oleandomycin, oxytetracycline, penicillin, procaine penicillin, sodium arsanilate, streptogramin, streptomycin, sulfamethazine, sulfaquinox-aline, sulfathiazole, tetracycline, tylosin, vancomycin, and virginiamycin;