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A fungus disease of the nails.



a disease of the nails caused by pathogenic fungi (seeDERMATOMYCOSES). Onychomycosis usually accompanies epidermophytosis; less commonly, trichophytosis, favus, candidiasis, and other fungal diseases. Onychomycosis, which rarely occurs as a separate disease, can arise in combination with fungal diseases of the skin and hair.

Acute inflammation is usually absent in onychomycosis. The nail plate becomes yellow, opaque, or brown, as well as brittle and thick: the nail often separates from the bed and becomes deformed. In some forms of onychomycosis, for example, when the accompanying disease is an epidermophytosis, all the nail plates are affected. In other forms, only a few nail plates are affected; for example, when trichophytosis is the accompanying disease, only the nails of the first and fifth toes have lesions. The pathological process may sometimes spread from the surrounding tissues to the nail plate. This occurs, for example, in onychomycosis that results from candidiasis, when the infection spreads from the borders of the nail.

Onychomycosis is treated by removing the nail plates with keratolytic plasters or with surgery and by applying antifungal agents. The disease is prevented by protecting the nail plates against injuries, treating microtraumas of the skin and nails with a 2 percent tincture of iodine, and by wearing shoes that fit properly. It is also important to control perspiration, to take proper hygienic care of the nails, and to wear slippers in baths, pools, and showers. On the public level, onychomycosis is prevented by disinfecting the patient’s personal belongings, by preventive checkups, and by inspection of public baths, pools, barbershops, and therapeutic baths. Cattle and other domestic animals are inspected for onychomycosis.


Sheklakov, N. D., and M. V. Milich. Gribkovye zabolevaniia cheloveka. Moscow, 1970.


References in periodicals archive ?
Conclusion: PAS staining of nail clippings for hyphae is a very sensitive method for diagnosis of onychomycosis as compared to KOH mount.
It has been shown that re- infection is a common occurrence in onychomycosis [49,50] probably occurring as the patient reacquires dermatophytic fomites from previously worn footwear and hosiery.
A total of 200 clinically diagnosed patients of onychomycosis were included in this study.
Nail dystrophy and desiccation contribute to onychomycosis.
If you think you have onychomycosis, it is important to see a dermatologist to be evaluated so other diseases can be ruled out and it can be treated effectively.
1999 Apr 17;318[7190]: 1031 -5) Of course, both of these systemic antifungals are used "off label" for children and adolescents with onychomycosis.
In this study, we aimed to assess onychomycosis and/or tinea pedis frequency in diabetic patients, and effects on the development of chronic complications, particularly foot ulcer.
Easy application of nail paints is also expected to drive demand for dermatophytic onychomycosis drugs.
This report provides comprehensive information on the therapeutic development for Onychomycosis (Tinea Unguium), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
2013 Dec; 148[6]: 603-8), as well as that of others, indicates tinea pedis and onychomycosis in diabetic patients often goes undiagnosed, ignored, or inadequately treated.
Patients who have early onychomycosis can be effectively treated with once-daily efinaconazole topical solution, 10%, according to data from more than 1,000 subjects.